@article{a763e3ccaecc4b8ca100af90d109349f,
title = "Evolution of the cohort study",
author = "Samet, {Jonathan M.} and Alvaro Mu{\~n}oz",
note = "Funding Information: Another landmark cohort study, the investigation of the atomic bomb survivors in Hiroshima and Nagasaki, addressed the consequences of ionizing radiation exposure. This population, a group having a unique and instantaneous exposure, contrasts with the Framingham Study, a general population study of several diseases that tests multiple hypotheses. The two bombs were dropped in 1945, and investigation of the medical consequences began almost immediately thereafter (26). By 1946, a decision had been made to conduct long-term studies, and the Atomic Bomb Casualty Commission was established in 1947. In 1975, this organization was replaced by the Radiation Effects Research Foundation, still operating, which is funded jointly by the United States and Japan. Acute and chronic effects of radiation exposure were already known but there was little quantitative information available on the risks of radiation. Radiation doses from the blasts were eventually reconstructed and selected survivors were entered into a cohort study that included periodic medical examinations.",
year = "1998",
doi = "10.1093/oxfordjournals.epirev.a017964",
language = "English (US)",
volume = "20",
pages = "1--14",
journal = "Epidemiologic reviews",
issn = "0193-936X",
publisher = "Oxford University Press",
number = "1",
}