Evolution of outer retinal folds occurring after vitrectomy for retinal detachment repair

Roberto Dell'Omo, H. Stevie Tan, Reinier O. Schlingemann, Heico M. Bijl, Sarit Y Lesnik Oberstein, Francesco Barca, Marco Mura

Research output: Contribution to journalArticle

Abstract

Purpose. To assess the evolution of outer retinal folds (ORFs) occurring after repair of rhegmatogenous retinal detachment (RRD) using spectral domain-optical coherence tomography (sd-OCT) and fundus autofluorescence (FAF), and to discuss their pathogenesis. Methods. Twenty patients were operated on with 25-gauge pars plana vitrectomy and 20% sulfur hexafluoride gas injection for primary macula-off RRD repair and were followed prospectively. Sd-OCT and FAF images were recorded at 1, 3 and 6 months postoperatively. Results. ORFs appeared on sd-OCT as hyperreflective lesions consisting of folded inner segment/outer segment of photore-ceptors band and external limiting membrane band. Corresponding lines of increased or decreased autofluorescence were observed on FAF. Over the follow-up, the thick hypoautofluorescent lines progressively evolved to thick hyperautofluorescent lines and to thin hyperautofluorescent lines and eventually disappeared. Concomitantly, OCT scans revealed that the corresponding hyperreflective lesions decreased in number, height, and size. In six cases FAF assessment at month 6 was precluded by cataract development. Conclusions. ORFs tend to resolve spontaneously within a few months from operation leaving no or subtle abnormalities at the level of the outer retinal layers. OCT is superior to FAF to follow the evolution of ORFs in phakic eyes. The following factors might be involved in ORFs pathogenesis: structural changes occurring in the detached retina, residual pockets of subretinal fluid after retinal reattachment, intravitreal gas, unintentional retinal translocation, and intraoperative or perioperative hypotony.

Original languageEnglish (US)
Pages (from-to)7928-7935
Number of pages8
JournalInvestigative Ophthalmology and Visual Science
Volume53
Issue number13
DOIs
StatePublished - Dec 2012
Externally publishedYes

Fingerprint

Vitrectomy
Optical Coherence Tomography
Retinal Detachment
Gases
Sulfur Hexafluoride
Subretinal Fluid
Temazepam
Cataract
Retina
Injections
Membranes

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Dell'Omo, R., Stevie Tan, H., Schlingemann, R. O., Bijl, H. M., Oberstein, S. Y. L., Barca, F., & Mura, M. (2012). Evolution of outer retinal folds occurring after vitrectomy for retinal detachment repair. Investigative Ophthalmology and Visual Science, 53(13), 7928-7935. https://doi.org/10.1167/iovs.12-10322

Evolution of outer retinal folds occurring after vitrectomy for retinal detachment repair. / Dell'Omo, Roberto; Stevie Tan, H.; Schlingemann, Reinier O.; Bijl, Heico M.; Oberstein, Sarit Y Lesnik; Barca, Francesco; Mura, Marco.

In: Investigative Ophthalmology and Visual Science, Vol. 53, No. 13, 12.2012, p. 7928-7935.

Research output: Contribution to journalArticle

Dell'Omo, R, Stevie Tan, H, Schlingemann, RO, Bijl, HM, Oberstein, SYL, Barca, F & Mura, M 2012, 'Evolution of outer retinal folds occurring after vitrectomy for retinal detachment repair', Investigative Ophthalmology and Visual Science, vol. 53, no. 13, pp. 7928-7935. https://doi.org/10.1167/iovs.12-10322
Dell'Omo, Roberto ; Stevie Tan, H. ; Schlingemann, Reinier O. ; Bijl, Heico M. ; Oberstein, Sarit Y Lesnik ; Barca, Francesco ; Mura, Marco. / Evolution of outer retinal folds occurring after vitrectomy for retinal detachment repair. In: Investigative Ophthalmology and Visual Science. 2012 ; Vol. 53, No. 13. pp. 7928-7935.
@article{921be674ee4a4c9ba47c1246b870390b,
title = "Evolution of outer retinal folds occurring after vitrectomy for retinal detachment repair",
abstract = "Purpose. To assess the evolution of outer retinal folds (ORFs) occurring after repair of rhegmatogenous retinal detachment (RRD) using spectral domain-optical coherence tomography (sd-OCT) and fundus autofluorescence (FAF), and to discuss their pathogenesis. Methods. Twenty patients were operated on with 25-gauge pars plana vitrectomy and 20{\%} sulfur hexafluoride gas injection for primary macula-off RRD repair and were followed prospectively. Sd-OCT and FAF images were recorded at 1, 3 and 6 months postoperatively. Results. ORFs appeared on sd-OCT as hyperreflective lesions consisting of folded inner segment/outer segment of photore-ceptors band and external limiting membrane band. Corresponding lines of increased or decreased autofluorescence were observed on FAF. Over the follow-up, the thick hypoautofluorescent lines progressively evolved to thick hyperautofluorescent lines and to thin hyperautofluorescent lines and eventually disappeared. Concomitantly, OCT scans revealed that the corresponding hyperreflective lesions decreased in number, height, and size. In six cases FAF assessment at month 6 was precluded by cataract development. Conclusions. ORFs tend to resolve spontaneously within a few months from operation leaving no or subtle abnormalities at the level of the outer retinal layers. OCT is superior to FAF to follow the evolution of ORFs in phakic eyes. The following factors might be involved in ORFs pathogenesis: structural changes occurring in the detached retina, residual pockets of subretinal fluid after retinal reattachment, intravitreal gas, unintentional retinal translocation, and intraoperative or perioperative hypotony.",
author = "Roberto Dell'Omo and {Stevie Tan}, H. and Schlingemann, {Reinier O.} and Bijl, {Heico M.} and Oberstein, {Sarit Y Lesnik} and Francesco Barca and Marco Mura",
year = "2012",
month = "12",
doi = "10.1167/iovs.12-10322",
language = "English (US)",
volume = "53",
pages = "7928--7935",
journal = "Investigative Ophthalmology and Visual Science",
issn = "0146-0404",
publisher = "Association for Research in Vision and Ophthalmology Inc.",
number = "13",

}

TY - JOUR

T1 - Evolution of outer retinal folds occurring after vitrectomy for retinal detachment repair

AU - Dell'Omo, Roberto

AU - Stevie Tan, H.

AU - Schlingemann, Reinier O.

AU - Bijl, Heico M.

AU - Oberstein, Sarit Y Lesnik

AU - Barca, Francesco

AU - Mura, Marco

PY - 2012/12

Y1 - 2012/12

N2 - Purpose. To assess the evolution of outer retinal folds (ORFs) occurring after repair of rhegmatogenous retinal detachment (RRD) using spectral domain-optical coherence tomography (sd-OCT) and fundus autofluorescence (FAF), and to discuss their pathogenesis. Methods. Twenty patients were operated on with 25-gauge pars plana vitrectomy and 20% sulfur hexafluoride gas injection for primary macula-off RRD repair and were followed prospectively. Sd-OCT and FAF images were recorded at 1, 3 and 6 months postoperatively. Results. ORFs appeared on sd-OCT as hyperreflective lesions consisting of folded inner segment/outer segment of photore-ceptors band and external limiting membrane band. Corresponding lines of increased or decreased autofluorescence were observed on FAF. Over the follow-up, the thick hypoautofluorescent lines progressively evolved to thick hyperautofluorescent lines and to thin hyperautofluorescent lines and eventually disappeared. Concomitantly, OCT scans revealed that the corresponding hyperreflective lesions decreased in number, height, and size. In six cases FAF assessment at month 6 was precluded by cataract development. Conclusions. ORFs tend to resolve spontaneously within a few months from operation leaving no or subtle abnormalities at the level of the outer retinal layers. OCT is superior to FAF to follow the evolution of ORFs in phakic eyes. The following factors might be involved in ORFs pathogenesis: structural changes occurring in the detached retina, residual pockets of subretinal fluid after retinal reattachment, intravitreal gas, unintentional retinal translocation, and intraoperative or perioperative hypotony.

AB - Purpose. To assess the evolution of outer retinal folds (ORFs) occurring after repair of rhegmatogenous retinal detachment (RRD) using spectral domain-optical coherence tomography (sd-OCT) and fundus autofluorescence (FAF), and to discuss their pathogenesis. Methods. Twenty patients were operated on with 25-gauge pars plana vitrectomy and 20% sulfur hexafluoride gas injection for primary macula-off RRD repair and were followed prospectively. Sd-OCT and FAF images were recorded at 1, 3 and 6 months postoperatively. Results. ORFs appeared on sd-OCT as hyperreflective lesions consisting of folded inner segment/outer segment of photore-ceptors band and external limiting membrane band. Corresponding lines of increased or decreased autofluorescence were observed on FAF. Over the follow-up, the thick hypoautofluorescent lines progressively evolved to thick hyperautofluorescent lines and to thin hyperautofluorescent lines and eventually disappeared. Concomitantly, OCT scans revealed that the corresponding hyperreflective lesions decreased in number, height, and size. In six cases FAF assessment at month 6 was precluded by cataract development. Conclusions. ORFs tend to resolve spontaneously within a few months from operation leaving no or subtle abnormalities at the level of the outer retinal layers. OCT is superior to FAF to follow the evolution of ORFs in phakic eyes. The following factors might be involved in ORFs pathogenesis: structural changes occurring in the detached retina, residual pockets of subretinal fluid after retinal reattachment, intravitreal gas, unintentional retinal translocation, and intraoperative or perioperative hypotony.

UR - http://www.scopus.com/inward/record.url?scp=84870548244&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84870548244&partnerID=8YFLogxK

U2 - 10.1167/iovs.12-10322

DO - 10.1167/iovs.12-10322

M3 - Article

VL - 53

SP - 7928

EP - 7935

JO - Investigative Ophthalmology and Visual Science

JF - Investigative Ophthalmology and Visual Science

SN - 0146-0404

IS - 13

ER -