Evolution of Neovascularization in Sickle Cell Retinopathy: A Prospective Fluorescein Angiographic Study

Motilal Raichand; Morton F. Goldberg; Krishan C. Nagpal; Michael H. Goldbaum; George K. Asdourian

doi:10.1001/archopht.1977.04450090065005

Evolution of Neovascularization in Sickle Cell Retinopathy: A Prospective Fluorescein Angiographic Study

Motilal Raichand, Morton F. Goldberg, Krishan C. Nagpal, Michael H. Goldbaum, George K. Asdourian

Research output: Contribution to journal › Article › peer-review

Abstract

With prospective observations we have documented by fluorescein angiography the development of retinal neovascularization in the eyes of patients with sickle cell-hemoglobin C disease (hemoglobin SC). In each patient, arteriolarvenular (AV) anastomoses occurred before the development of neovascular sea fans. To our knowledge, this report constitutes the first such documentation in the literature. New sea fans from AV anastomoses appeared throughout an average interval of 18 months (range, 8 to 36 months) in approximately 21% of young adutls with hemoglobin SC. Each year approximately 14% of young patients with hemoglobin SC may develop retinal neovascularization.

Original language	English (US)
Pages (from-to)	1543-1552
Number of pages	10
Journal	Archives of ophthalmology
Volume	95
Issue number	9
DOIs	https://doi.org/10.1001/archopht.1977.04450090065005
State	Published - Sep 1977
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology

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title = "Evolution of Neovascularization in Sickle Cell Retinopathy: A Prospective Fluorescein Angiographic Study",

abstract = "With prospective observations we have documented by fluorescein angiography the development of retinal neovascularization in the eyes of patients with sickle cell-hemoglobin C disease (hemoglobin SC). In each patient, arteriolarvenular (AV) anastomoses occurred before the development of neovascular sea fans. To our knowledge, this report constitutes the first such documentation in the literature. New sea fans from AV anastomoses appeared throughout an average interval of 18 months (range, 8 to 36 months) in approximately 21% of young adutls with hemoglobin SC. Each year approximately 14% of young patients with hemoglobin SC may develop retinal neovascularization.",

author = "Motilal Raichand and Goldberg, {Morton F.} and Nagpal, {Krishan C.} and Goldbaum, {Michael H.} and Asdourian, {George K.}",

year = "1977",

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AU - Goldbaum, Michael H.

AU - Asdourian, George K.

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