Evidence that serum potassium is not the etiological agent in ventricular fibrillation following coronary artery occlusion

Jack Wexler, Howard H. Patt

Research output: Contribution to journalArticle

Abstract

1. 1. Elevation of the concentration of potassium in the coronary sinus occurred only in 33 per cent of 69 dogs after ligation of a major coronary artery. 2. 2. Eighteen of the 23 dogs (78 per cent) with an elevation of the level of potassium in the coronary sinus blood maintained a normal sinus rhythm throughout the experimental period. 3. 3. Of 12 animals which developed ventricular fibrillation after coronary artery ligation, only 3 showed a significant elevation of the concentration of potassium in the coronary sinus. The other 9 failed to show any increase in the level of potassium in the coronary sinus. None of the 12 showed an increase in the concentration of potassium in the femoral artery. 4. 4. These results fail to support the thesis that an increase in the levels of serum potassium incites ventricular fibrillation after coronary artery ligation.

Original languageEnglish (US)
Pages (from-to)618-623
Number of pages6
JournalAmerican Heart Journal
Volume60
Issue number4
StatePublished - Oct 1960

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Coronary Occlusion
Ventricular Fibrillation
Coronary Vessels
Potassium
Coronary Sinus
Serum
Ligation
Dogs
Femoral Artery

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Medicine(all)

Cite this

Evidence that serum potassium is not the etiological agent in ventricular fibrillation following coronary artery occlusion. / Wexler, Jack; Patt, Howard H.

In: American Heart Journal, Vol. 60, No. 4, 10.1960, p. 618-623.

Research output: Contribution to journalArticle

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