Evidence of hormonal basis for improved survival among females with trauma-associated shock: an analysis of the National Trauma Data Bank.

Adil H. Haider; Joseph G. Crompton; David C. Chang; David T. Efron; Elliott R. Haut; Neal Handly; Edward E. Cornwell

Evidence of hormonal basis for improved survival among females with trauma-associated shock: an analysis of the National Trauma Data Bank.

Adil H. Haider, Joseph G. Crompton, David C. Chang, David T. Efron, Elliott R. Haut, Neal Handly, Edward E. Cornwell

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND: Basic science research suggests that sex hormones affect survival after traumatic shock. This study sought to determine the independent effect of gender on mortality among trauma patients in different hormone-related age groups. METHODS: Review of severely injured trauma patients with shock included in the National Trauma Databank. Patients were stratified into three groups on the basis of likely hormonal status: prehormonal (age, 0-12 years), hormonal (age,13-64 years), and posthormonal (age, ≥ 65 years). Multiple logistic regression was used to analyze the independent effect of gender on mortality in each group, adjusting for anatomic and physiologic injury severity. RESULTS: A total of 48,394 patients met our inclusion criteria (Injury Severity Score ≥ 16 and systolic blood pressure

Original language	English (US)
Pages (from-to)	537-540
Number of pages	4
Journal	Journal of Trauma - Injury, Infection and Critical Care
Volume	69
Issue number	3
State	Published - Sep 2010
Externally published	Yes

ASJC Scopus subject areas

General Medicine

Cite this

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title = "Evidence of hormonal basis for improved survival among females with trauma-associated shock: an analysis of the National Trauma Data Bank.",

abstract = "BACKGROUND: Basic science research suggests that sex hormones affect survival after traumatic shock. This study sought to determine the independent effect of gender on mortality among trauma patients in different hormone-related age groups. METHODS: Review of severely injured trauma patients with shock included in the National Trauma Databank. Patients were stratified into three groups on the basis of likely hormonal status: prehormonal (age, 0-12 years), hormonal (age,13-64 years), and posthormonal (age, ≥ 65 years). Multiple logistic regression was used to analyze the independent effect of gender on mortality in each group, adjusting for anatomic and physiologic injury severity. RESULTS: A total of 48,394 patients met our inclusion criteria (Injury Severity Score ≥ 16 and systolic blood pressure ",

author = "Haider, {Adil H.} and Crompton, {Joseph G.} and Chang, {David C.} and Efron, {David T.} and Haut, {Elliott R.} and Neal Handly and Cornwell, {Edward E.}",

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language = "English (US)",

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pages = "537--540",

journal = "Journal of Trauma - Injury, Infection and Critical Care",

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TY - JOUR

T1 - Evidence of hormonal basis for improved survival among females with trauma-associated shock

T2 - an analysis of the National Trauma Data Bank.

AU - Haider, Adil H.

AU - Crompton, Joseph G.

AU - Chang, David C.

AU - Efron, David T.

AU - Haut, Elliott R.

AU - Handly, Neal

AU - Cornwell, Edward E.

PY - 2010/9

Y1 - 2010/9

N2 - BACKGROUND: Basic science research suggests that sex hormones affect survival after traumatic shock. This study sought to determine the independent effect of gender on mortality among trauma patients in different hormone-related age groups. METHODS: Review of severely injured trauma patients with shock included in the National Trauma Databank. Patients were stratified into three groups on the basis of likely hormonal status: prehormonal (age, 0-12 years), hormonal (age,13-64 years), and posthormonal (age, ≥ 65 years). Multiple logistic regression was used to analyze the independent effect of gender on mortality in each group, adjusting for anatomic and physiologic injury severity. RESULTS: A total of 48,394 patients met our inclusion criteria (Injury Severity Score ≥ 16 and systolic blood pressure

AB - BACKGROUND: Basic science research suggests that sex hormones affect survival after traumatic shock. This study sought to determine the independent effect of gender on mortality among trauma patients in different hormone-related age groups. METHODS: Review of severely injured trauma patients with shock included in the National Trauma Databank. Patients were stratified into three groups on the basis of likely hormonal status: prehormonal (age, 0-12 years), hormonal (age,13-64 years), and posthormonal (age, ≥ 65 years). Multiple logistic regression was used to analyze the independent effect of gender on mortality in each group, adjusting for anatomic and physiologic injury severity. RESULTS: A total of 48,394 patients met our inclusion criteria (Injury Severity Score ≥ 16 and systolic blood pressure

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M3 - Article

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SN - 0022-5282

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Evidence of hormonal basis for improved survival among females with trauma-associated shock: an analysis of the National Trauma Data Bank.

Abstract

ASJC Scopus subject areas

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