Evidence of hormonal basis for improved survival among females with trauma-associated shock: an analysis of the National Trauma Data Bank.

Adil H. Haider, Joseph G. Crompton, David C. Chang, David T. Efron, Elliott R. Haut, Neal Handly, Edward E. Cornwell

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: Basic science research suggests that sex hormones affect survival after traumatic shock. This study sought to determine the independent effect of gender on mortality among trauma patients in different hormone-related age groups. METHODS: Review of severely injured trauma patients with shock included in the National Trauma Databank. Patients were stratified into three groups on the basis of likely hormonal status: prehormonal (age, 0-12 years), hormonal (age,13-64 years), and posthormonal (age, ≥ 65 years). Multiple logistic regression was used to analyze the independent effect of gender on mortality in each group, adjusting for anatomic and physiologic injury severity. RESULTS: A total of 48,394 patients met our inclusion criteria (Injury Severity Score ≥ 16 and systolic blood pressure

Original languageEnglish (US)
Pages (from-to)537-540
Number of pages4
JournalJournal of Trauma - Injury, Infection and Critical Care
Volume69
Issue number3
StatePublished - Sep 2010
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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