@article{9a7cceb37caf4e3a960a7debbf67b5ce,
title = "Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12",
abstract = "We carried out a fine-mapping study in the HNF1B gene at 17q12 in two study populations and identified a second locus associated with prostate cancer risk, ∼26 kb centromeric to the first known locus (rs4430796); these loci are separated by a recombination hot spot. We confirmed the association with a SNP in the second locus (rs11649743) in five additional populations, with P = 1.7 × 10-9 for an allelic test of the seven studies combined. The association at each SNP remained significant after adjustment for the other SNP.",
author = "Jielin Sun and Zheng, {Siqun Lilly} and Fredrik Wiklund and Isaacs, {Sarah D.} and Purcell, {Lina D.} and Zhengrong Gao and Hsu, {Fang Chi} and Kim, {Seong Tae} and Wennuan Liu and Yi Zhu and P{\"a}r Stattin and Adami, {Hans Olov} and Wiley, {Kathleen E.} and Latchezar Dimitrov and Jishan Sun and Tao Li and Turner, {Aubrey R.} and Adams, {Tamara S.} and Jan Adolfsson and Johansson, {Jan Erik} and James Lowey and Trock, {Bruce J.} and Partin, {Alan W.} and Walsh, {Patrick C.} and Trent, {Jeffrey M.} and David Duggan and John Carpten and Chang, {Bao Li} and Henrik Gr{\"o}nberg and Isaacs, {William B.} and Jianfeng Xu",
year = "2008",
month = oct,
doi = "10.1038/ng.214",
language = "English (US)",
volume = "40",
pages = "1153--1155",
journal = "Nature genetics",
issn = "1061-4036",
publisher = "Nature Publishing Group",
number = "10",
}