TY - JOUR
T1 - Evidence for reliability, validity and usefulness of the Medical Outcomes Study HIV Health Survey (MOS-HIV)
AU - Wu, A. W.
AU - Revicki, D. A.
AU - Jacobson, D.
AU - Malitz, F. E.
N1 - Funding Information:
Supported in part by grants from the AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases, the Agency for Health Care Policy and Research HS07824, Glaxo Wellcome the IQoLA Project at the Health Institute and by cooperative agreements with the National Eye Institute and the Johns Hopkins University School of Hygiene and Public Health (U10 EY 0850), the Johns Hopkins University School of Medicine (U10 EY 08052) and the National Institute of Allergy and Infectious Diseases (U01 AI 27668) with Johns Hopkins University.
Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 1997
Y1 - 1997
N2 - The Medical Outcomes Study HIV Health Survey (MOS-HIV) is a brief, comprehensive measure of health-related quality of life (HRQoL) used extensively in human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS). The 35-item questionnaire includes ten dimensions (health perceptions, pain, physical, role, social and cognitive functioning, mental health, energy, health distress and quality of life (QoL)) and takes approximately 5 minutes to complete. Subscales are scored on a 0-100 scale (a higher score indicates better health) and physical and mental health summary scores can be generated. The MOS-HIV has been shown to be internally consistent, correlate with concurrent measures of health, discriminate between distinct groups, predict future outcomes and be responsive to changes over time. Limited experience suggests acceptable reliability and validity in women, injecting drug users and African- American and lower socioeconomic status patients. The MOS-HIV is available in 14 languages and has been included as a secondary outcome measure in numerous clinical trials for all stages of disease. In several studies it has detected significant differences between treatments; in some cases concordant with conventional end-points and, in others, discordant. The interpretation of scores is facilitated by an explanation in terms meaningful to the intended audience. Research is needed to compare the MOS- HIV to other strategies for HRQoL assessment in early HIV disease.
AB - The Medical Outcomes Study HIV Health Survey (MOS-HIV) is a brief, comprehensive measure of health-related quality of life (HRQoL) used extensively in human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS). The 35-item questionnaire includes ten dimensions (health perceptions, pain, physical, role, social and cognitive functioning, mental health, energy, health distress and quality of life (QoL)) and takes approximately 5 minutes to complete. Subscales are scored on a 0-100 scale (a higher score indicates better health) and physical and mental health summary scores can be generated. The MOS-HIV has been shown to be internally consistent, correlate with concurrent measures of health, discriminate between distinct groups, predict future outcomes and be responsive to changes over time. Limited experience suggests acceptable reliability and validity in women, injecting drug users and African- American and lower socioeconomic status patients. The MOS-HIV is available in 14 languages and has been included as a secondary outcome measure in numerous clinical trials for all stages of disease. In several studies it has detected significant differences between treatments; in some cases concordant with conventional end-points and, in others, discordant. The interpretation of scores is facilitated by an explanation in terms meaningful to the intended audience. Research is needed to compare the MOS- HIV to other strategies for HRQoL assessment in early HIV disease.
KW - HIV
KW - MOS-HIV
KW - Reliability
KW - Validity
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U2 - 10.1023/A:1018451930750
DO - 10.1023/A:1018451930750
M3 - Article
C2 - 9330549
AN - SCOPUS:0030847865
SN - 0962-9343
VL - 6
SP - 481
EP - 493
JO - Quality of Life Research
JF - Quality of Life Research
IS - 6
ER -