Evidence for linkage to chromosome 13q32 in an independent sample of schizophrenia families

J. G. Mulle, J. A. McDonough, K. V. Chowdari, V. Nimgaonkar, A. Chakravarti

Research output: Contribution to journalArticlepeer-review

Abstract

Linkage analysis has identified chromosome 13q32 as a putative susceptibility locus for schizophrenia, although this region has not been replicated in all studies. The authors focused on this region, and investigated evidence for linkage in a sample of sib-pair pedigrees affected with schizophrenia. Nonparametric analysis revealed significant evidence for linkage at this region. This finding is consistent with previous reports of linkage, and enhances the plausibility of chromosome 13q32 as a true schizophrenia susceptibility locus.

Original languageEnglish (US)
Pages (from-to)429-431+423
JournalMolecular psychiatry
Volume10
Issue number5
DOIs
StatePublished - May 2005

ASJC Scopus subject areas

  • Molecular Biology
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience

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