Evidence for cellular immune mechanisms in hyperacute rejection of renal allografts in miniature swine

R. L. Kirkman, M. W. Flye, G. M. Williams, R. B. Colvin, D. H. Sachs

Research output: Contribution to journalArticlepeer-review

Abstract

In a series of renal allografts, performed between MHC-identical miniature swine presensitized by skin grafts, we have found hyperacute or markedly accelerated rejection in the absence of detectable antidonor antibody. In vitro assays of reactive lymphocytes suggested that cellular mechanisms were involved in hyperacute rejection in these animals.

Original languageEnglish (US)
Pages (from-to)790-792
Number of pages3
JournalTransplantation proceedings
Volume11
Issue number1
StatePublished - Nov 27 1979

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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