Evidence-based medicine in the treatment of peritoneal carcinomatosis: Past, present, and future

Aviram Nissan, Alexander Stojadinovic, Alfredo Garofalo, Jesus Esquivel, Pompiliu Piso

Research output: Contribution to journalArticle


The current treatment of peritoneal surface malignancies (PSMs) is moving from a nihilistic approach, into a combined modality approach offering selected patients long-term survival. As primary PSM are rare, extrapolation of data from clinical trials of related disease is necessary to develop treatment guidelines. Secondary PSM are more common, and therefore, treatment guidelines should be developed based on prospective clinical trials. We reviewed the published and ongoing clinical trials studying the treatment of PSM.

Original languageEnglish (US)
Pages (from-to)335-344
Number of pages10
JournalJournal of Surgical Oncology
Issue number4
StatePublished - Sep 15 2009



  • Carcinomatosis
  • Clinical trial
  • Cytoreduction
  • Hyperthermic chemotherapy
  • Peritoneal surface malignancies

ASJC Scopus subject areas

  • Surgery
  • Oncology

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