Evidence-based management guidelines on peyronie's disease

Eric Chung, David Ralph, Ates Kagioglu, Guilio Garaffa, Ahmed Shamsodini, Trinity Bivalacqua, Sidney Glina, Lawrence Hakim, Hossein Sadeghi-Nejad, Gregory Broderick

Research output: Contribution to journalArticle

Abstract

Introduction: Despite recent advances in our knowledge and treatment strategies in Peyronie's Disease (PD), much remained unknown about this disease. Aim: To provide a clinical framework and key guideline statements to assist clinicians in an evidence-based management of PD. Methods: A systematic literature search was conducted to identify published literature relevant to PD. The search included all relevant articles published up to June 2015, including preclinical studies and published guidelines. References used in the text were assessed according to their level of evidence, and guideline recommendations were graded based on the Oxford Centre for Evidence-Based Medicine Levels of Evidence. Owing to the paucity of larger series and randomized placebo-controlled trials with regard to surgical intervention, guideline statements are provided as clinical principle or expert opinion. Main Outcome Measures: This literature was discussed at a panel meeting, and selected articles with the highest evidence available were used to create consensus guideline statements for the Fourth International Consultation on Sexual Medicine guidelines on PD. Results: In addition to existing Third International Consultation on Sexual Medicine guidelines on PD, seven new summary recommendations were created. Conclusion: A greater understanding of the scientific basis of PD is greatly needed to address our understanding of the pathophysiology, clinical epidemiology, psychosocial, and diagnostic assessment as well as treatment strategies.

Original languageEnglish (US)
Pages (from-to)905-923
Number of pages19
JournalJournal of Sexual Medicine
Volume13
Issue number6
DOIs
StatePublished - Jun 1 2016

Fingerprint

Penile Induration
Guidelines
Referral and Consultation
Medicine
Evidence-Based Medicine
Expert Testimony
Epidemiology
Randomized Controlled Trials
Placebos
Outcome Assessment (Health Care)
Therapeutics

Keywords

  • Clinical Evidence
  • Management Guideline
  • Penile Surgery
  • Peyronie's Disease
  • Summary Recommendation
  • Treatment Outcomes

ASJC Scopus subject areas

  • Urology
  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Chung, E., Ralph, D., Kagioglu, A., Garaffa, G., Shamsodini, A., Bivalacqua, T., ... Broderick, G. (2016). Evidence-based management guidelines on peyronie's disease. Journal of Sexual Medicine, 13(6), 905-923. https://doi.org/10.1016/j.jsxm.2016.04.062

Evidence-based management guidelines on peyronie's disease. / Chung, Eric; Ralph, David; Kagioglu, Ates; Garaffa, Guilio; Shamsodini, Ahmed; Bivalacqua, Trinity; Glina, Sidney; Hakim, Lawrence; Sadeghi-Nejad, Hossein; Broderick, Gregory.

In: Journal of Sexual Medicine, Vol. 13, No. 6, 01.06.2016, p. 905-923.

Research output: Contribution to journalArticle

Chung, E, Ralph, D, Kagioglu, A, Garaffa, G, Shamsodini, A, Bivalacqua, T, Glina, S, Hakim, L, Sadeghi-Nejad, H & Broderick, G 2016, 'Evidence-based management guidelines on peyronie's disease', Journal of Sexual Medicine, vol. 13, no. 6, pp. 905-923. https://doi.org/10.1016/j.jsxm.2016.04.062
Chung, Eric ; Ralph, David ; Kagioglu, Ates ; Garaffa, Guilio ; Shamsodini, Ahmed ; Bivalacqua, Trinity ; Glina, Sidney ; Hakim, Lawrence ; Sadeghi-Nejad, Hossein ; Broderick, Gregory. / Evidence-based management guidelines on peyronie's disease. In: Journal of Sexual Medicine. 2016 ; Vol. 13, No. 6. pp. 905-923.
@article{8d14204d813544e2bf3462ab2af2fa37,
title = "Evidence-based management guidelines on peyronie's disease",
abstract = "Introduction: Despite recent advances in our knowledge and treatment strategies in Peyronie's Disease (PD), much remained unknown about this disease. Aim: To provide a clinical framework and key guideline statements to assist clinicians in an evidence-based management of PD. Methods: A systematic literature search was conducted to identify published literature relevant to PD. The search included all relevant articles published up to June 2015, including preclinical studies and published guidelines. References used in the text were assessed according to their level of evidence, and guideline recommendations were graded based on the Oxford Centre for Evidence-Based Medicine Levels of Evidence. Owing to the paucity of larger series and randomized placebo-controlled trials with regard to surgical intervention, guideline statements are provided as clinical principle or expert opinion. Main Outcome Measures: This literature was discussed at a panel meeting, and selected articles with the highest evidence available were used to create consensus guideline statements for the Fourth International Consultation on Sexual Medicine guidelines on PD. Results: In addition to existing Third International Consultation on Sexual Medicine guidelines on PD, seven new summary recommendations were created. Conclusion: A greater understanding of the scientific basis of PD is greatly needed to address our understanding of the pathophysiology, clinical epidemiology, psychosocial, and diagnostic assessment as well as treatment strategies.",
keywords = "Clinical Evidence, Management Guideline, Penile Surgery, Peyronie's Disease, Summary Recommendation, Treatment Outcomes",
author = "Eric Chung and David Ralph and Ates Kagioglu and Guilio Garaffa and Ahmed Shamsodini and Trinity Bivalacqua and Sidney Glina and Lawrence Hakim and Hossein Sadeghi-Nejad and Gregory Broderick",
year = "2016",
month = "6",
day = "1",
doi = "10.1016/j.jsxm.2016.04.062",
language = "English (US)",
volume = "13",
pages = "905--923",
journal = "Journal of Sexual Medicine",
issn = "1743-6095",
publisher = "Wiley-Blackwell",
number = "6",

}

TY - JOUR

T1 - Evidence-based management guidelines on peyronie's disease

AU - Chung, Eric

AU - Ralph, David

AU - Kagioglu, Ates

AU - Garaffa, Guilio

AU - Shamsodini, Ahmed

AU - Bivalacqua, Trinity

AU - Glina, Sidney

AU - Hakim, Lawrence

AU - Sadeghi-Nejad, Hossein

AU - Broderick, Gregory

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Introduction: Despite recent advances in our knowledge and treatment strategies in Peyronie's Disease (PD), much remained unknown about this disease. Aim: To provide a clinical framework and key guideline statements to assist clinicians in an evidence-based management of PD. Methods: A systematic literature search was conducted to identify published literature relevant to PD. The search included all relevant articles published up to June 2015, including preclinical studies and published guidelines. References used in the text were assessed according to their level of evidence, and guideline recommendations were graded based on the Oxford Centre for Evidence-Based Medicine Levels of Evidence. Owing to the paucity of larger series and randomized placebo-controlled trials with regard to surgical intervention, guideline statements are provided as clinical principle or expert opinion. Main Outcome Measures: This literature was discussed at a panel meeting, and selected articles with the highest evidence available were used to create consensus guideline statements for the Fourth International Consultation on Sexual Medicine guidelines on PD. Results: In addition to existing Third International Consultation on Sexual Medicine guidelines on PD, seven new summary recommendations were created. Conclusion: A greater understanding of the scientific basis of PD is greatly needed to address our understanding of the pathophysiology, clinical epidemiology, psychosocial, and diagnostic assessment as well as treatment strategies.

AB - Introduction: Despite recent advances in our knowledge and treatment strategies in Peyronie's Disease (PD), much remained unknown about this disease. Aim: To provide a clinical framework and key guideline statements to assist clinicians in an evidence-based management of PD. Methods: A systematic literature search was conducted to identify published literature relevant to PD. The search included all relevant articles published up to June 2015, including preclinical studies and published guidelines. References used in the text were assessed according to their level of evidence, and guideline recommendations were graded based on the Oxford Centre for Evidence-Based Medicine Levels of Evidence. Owing to the paucity of larger series and randomized placebo-controlled trials with regard to surgical intervention, guideline statements are provided as clinical principle or expert opinion. Main Outcome Measures: This literature was discussed at a panel meeting, and selected articles with the highest evidence available were used to create consensus guideline statements for the Fourth International Consultation on Sexual Medicine guidelines on PD. Results: In addition to existing Third International Consultation on Sexual Medicine guidelines on PD, seven new summary recommendations were created. Conclusion: A greater understanding of the scientific basis of PD is greatly needed to address our understanding of the pathophysiology, clinical epidemiology, psychosocial, and diagnostic assessment as well as treatment strategies.

KW - Clinical Evidence

KW - Management Guideline

KW - Penile Surgery

KW - Peyronie's Disease

KW - Summary Recommendation

KW - Treatment Outcomes

UR - http://www.scopus.com/inward/record.url?scp=84969168228&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84969168228&partnerID=8YFLogxK

U2 - 10.1016/j.jsxm.2016.04.062

DO - 10.1016/j.jsxm.2016.04.062

M3 - Article

C2 - 27215686

AN - SCOPUS:84969168228

VL - 13

SP - 905

EP - 923

JO - Journal of Sexual Medicine

JF - Journal of Sexual Medicine

SN - 1743-6095

IS - 6

ER -