Event-related potential activity in the basal ganglia differentiates rewards from nonrewards: Temporospatial principal components analysis and source localization of the feedback negativity

Dan Foti, Anna Weinberg, Joseph Dien, Greg Hajcak

Research output: Contribution to journalArticlepeer-review

Abstract

Event-related potential studies of reward processing have consistently identified the feedback negativity (FN), an early neural response that differentiates feedback indicating unfavorable versus favorable outcomes. Several important questions remain, however, about the nature of this response. In this study, the FN was recorded in response to monetary gains and losses during a laboratory gambling task, and temporospatial principal components analysis was used to separate the FN from overlapping responses. The FN was identified as a positive deflection at frontocentral recording sites that was enhanced for rewards compared with nonrewards. Furthermore, source localization techniques identified the striatum as a likely neural generator. These data indicate that this apparent FN reflects increased striatal activation in response to favorable outcomes that is reduced or absent for unfavorable outcomes, thereby providing unique information about the timing and nature of basal ganglia activity related to reward processing.

Original languageEnglish (US)
Pages (from-to)2207-2216
Number of pages10
JournalHuman Brain Mapping
Volume32
Issue number12
DOIs
StatePublished - Dec 2011

Keywords

  • Corpus striatum
  • Event-related potentials
  • Putamen
  • Reinforcement
  • Visual evoked potentials

ASJC Scopus subject areas

  • Anatomy
  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Clinical Neurology

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