Evaluation of topical ibuprofen cream in the treatment of acute ankle sprains

J. Campbell, T. Dunn

Research output: Contribution to journalArticlepeer-review

45 Scopus citations


One hundred patients who presented to the accident and emergency (A and E) department with an acute ankle sprain were entered into a study to determine the efficacy of topical ibuprofen cream by using a double-blind placebo controlled design in a single type of soft-tissue injury. The subjects were given either topical ibuprofen cream or a placebo cream in addition to the standard management of the department. Patients kept diaries recording walking ability and pain visual analogue scales for resting, standing and walking. A total of 51 patients returned diaries that were suitable for analysis. Patients using the topical ibuprofen cream had significant reduction in pain scores over the first 48 h of treatment.

Original languageEnglish (US)
Pages (from-to)178-182
Number of pages5
JournalJournal of Accident and Emergency Medicine
Issue number3
StatePublished - 1994
Externally publishedYes


  • Ankle sprain
  • Ibuprofen
  • Topical

ASJC Scopus subject areas

  • Medicine(all)


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