Evaluation of the enzyme-linked immunoelectrotransfer blot (EITB) for ovine hydatidosis relative to age and cyst characteristics in naturally infected sheep

Erica L. Dueger, Manuela Verastegui, Robert H. Gilman

Research output: Contribution to journalArticlepeer-review

Abstract

An enzyme-linked immunoelectrotransfer blot (EITB) for ovine echinococcosis was evaluated in an endemic area of the Peruvian central sierra. An overall test sensitivity of 91.4% was determined for 199 sheep. EITB sensitivity reached a plateau of nearly 100% at 3 years of age, while the prevalence of cystic disease peaked at 95% in sheep ≥6 years of age. In this highly endemic area, 61.7% of sheep without detectable cystic disease at necropsy (n=47) had positive EITB results. Relationships between EITB sensitivity, age, and cyst location, size, number, type, fertility, and viability were evaluated with logistic regression models. EITB sensitivity increased 14-fold in sheep with calcified cysts and 4-fold for each 1cm increase in pulmonary cyst size.

Original languageEnglish (US)
Pages (from-to)285-293
Number of pages9
JournalVeterinary Parasitology
Volume114
Issue number4
DOIs
StatePublished - Jun 25 2003

Keywords

  • Echinococcus granulosus
  • Enzyme-linked immunoelectrotransfer blot (EITB)
  • Hydatid
  • Peru
  • Sheep

ASJC Scopus subject areas

  • Parasitology
  • veterinary(all)

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