Evaluation of sterile uveitis after iris-fixated phakic intraocular lens implantation

Mohamadreza Sedaghat, Mehran Zarei-Ghanavati, Mohammad Reza Ansari-Astaneh, Virag Patel, Shameema Sikder

Research output: Contribution to journalArticle

Abstract

Purpose: To evaluate the clinical features, and visual outcomes of sterile uveitis after iris-fixated phakic intraocular lens implantation (pIOLs) (Artisan-Artiflex® and Verisyse-Veriflex® ). Material and Methods: In this retrospective non-comparative case series, the medical records of 117 eyes implanted with Artisan-Artiflex® (Ophtec BV, Groningen, Netherlands) and Verisyse-Veriflex® (AMO, Santa Ana, CA) iris claw phakic IOLs were analyzed for postimplantation sterile uveitis. The mean age of the 87 patients included in the study was 27.27.4 years. Of these patients, 56 (64.3%) were men and 31 (35.6%) were women. Patient age, gender, IOL brand type, refractive error, optic diameter, unilateral vs bilateral implantation, and anterior chamber depth were analyzed. Features of uveitis, uncorrected and best corrected visual acuity (VA) at presentation and at follow-up visits were examined. The mean follow-up time was 14.6 months (range: 6-37 months). Results: Clinically significant uveitis was observed in 12 of 117 eyes (10.3%) in a total of ten patients. Of these ten patients, four (40%) were women and six (60%) were men, and the mean age was 25.1 ± 5.3 years (range: 18-36 years). Among those with bilateral implantation, 6.9% of patients developed bilateral uveitis, while 13.8% (4 of the 29 implanted bilaterally) developed unilateral uveitis. Foldable pIOL implantation was the only variable associated with the development of uveitis (P=.03). Conclusion: Although the prognosis is usually benign, sterile uveitis occurred in 10.3% of patients after iris-fixated pIOL implantation. The implantation of a foldable pIOL was the only variable associated with sterile uveitis. Appropriate medical management can be effective treatment, without the need for pIOL replacement.

Original languageEnglish (US)
Pages (from-to)199-203
Number of pages5
JournalMiddle East African Journal of Ophthalmology
Volume19
Issue number2
DOIs
StatePublished - Apr 2012

Fingerprint

Phakic Intraocular Lenses
Intraocular Lens Implantation
Uveitis
Iris
Hoof and Claw
Refractive Errors
Anterior Chamber
Netherlands
Visual Acuity
Medical Records

Keywords

  • Artiflex®
  • Artisan®
  • Complications
  • Phakic Intraocular Lens
  • Uveitis
  • Veriflex®
  • Verisyse®

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Evaluation of sterile uveitis after iris-fixated phakic intraocular lens implantation. / Sedaghat, Mohamadreza; Zarei-Ghanavati, Mehran; Ansari-Astaneh, Mohammad Reza; Patel, Virag; Sikder, Shameema.

In: Middle East African Journal of Ophthalmology, Vol. 19, No. 2, 04.2012, p. 199-203.

Research output: Contribution to journalArticle

Sedaghat, Mohamadreza ; Zarei-Ghanavati, Mehran ; Ansari-Astaneh, Mohammad Reza ; Patel, Virag ; Sikder, Shameema. / Evaluation of sterile uveitis after iris-fixated phakic intraocular lens implantation. In: Middle East African Journal of Ophthalmology. 2012 ; Vol. 19, No. 2. pp. 199-203.
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N2 - Purpose: To evaluate the clinical features, and visual outcomes of sterile uveitis after iris-fixated phakic intraocular lens implantation (pIOLs) (Artisan-Artiflex® and Verisyse-Veriflex® ). Material and Methods: In this retrospective non-comparative case series, the medical records of 117 eyes implanted with Artisan-Artiflex® (Ophtec BV, Groningen, Netherlands) and Verisyse-Veriflex® (AMO, Santa Ana, CA) iris claw phakic IOLs were analyzed for postimplantation sterile uveitis. The mean age of the 87 patients included in the study was 27.27.4 years. Of these patients, 56 (64.3%) were men and 31 (35.6%) were women. Patient age, gender, IOL brand type, refractive error, optic diameter, unilateral vs bilateral implantation, and anterior chamber depth were analyzed. Features of uveitis, uncorrected and best corrected visual acuity (VA) at presentation and at follow-up visits were examined. The mean follow-up time was 14.6 months (range: 6-37 months). Results: Clinically significant uveitis was observed in 12 of 117 eyes (10.3%) in a total of ten patients. Of these ten patients, four (40%) were women and six (60%) were men, and the mean age was 25.1 ± 5.3 years (range: 18-36 years). Among those with bilateral implantation, 6.9% of patients developed bilateral uveitis, while 13.8% (4 of the 29 implanted bilaterally) developed unilateral uveitis. Foldable pIOL implantation was the only variable associated with the development of uveitis (P=.03). Conclusion: Although the prognosis is usually benign, sterile uveitis occurred in 10.3% of patients after iris-fixated pIOL implantation. The implantation of a foldable pIOL was the only variable associated with sterile uveitis. Appropriate medical management can be effective treatment, without the need for pIOL replacement.

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