Evaluation of seasonal patterns of Kawasaki Syndrome- and rotavirus-associated hospitalizations in California and New York, 2000-2005

Adam MacNeil; Robert C. Holman; Krista L. Yorita; Claudia A. Steiner; Umesh D. Parashar; Ermias D. Belay

doi:10.1186/1471-2431-9-65

Evaluation of seasonal patterns of Kawasaki Syndrome- and rotavirus-associated hospitalizations in California and New York, 2000-2005

Adam MacNeil, Robert C. Holman, Krista L. Yorita, Claudia A. Steiner, Umesh D. Parashar, Ermias D. Belay

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Background: Kawasaki Syndrome (KS) is an uncommon childhood disease with unknown etiology. It has been suggested that rotavirus infection may play a causative role in the development of KS. Methods: To examine potential temporal associations between KS and rotavirus infection, seasonal patterns of KS- and rotavirus-associated hospitalizations among children in California and New York during 2000-2005 were compared. Results: Rotavirus hospital admissions were markedly winter seasonal, with very few summer hospitalizations. KS hospitalizations occurred year-round but also peaked slightly during winter and spring. Conclusion: The strong winter seasonal pattern of rotavirus clearly differed from the year-round pattern of KS hospitalizations. While the present study cannot completely rule out rotavirus as having a role in the development of KS, other agents must be involved in the etiology of KS.

Original language	English (US)
Article number	65
Pages (from-to)	65
Number of pages	1
Journal	BMC Pediatrics
Volume	9
DOIs	https://doi.org/10.1186/1471-2431-9-65
State	Published - Oct 16 2009
Externally published	Yes

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1186/1471-2431-9-65

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@article{34eb864e100f4e6c8d43ef3f661325ca,

title = "Evaluation of seasonal patterns of Kawasaki Syndrome- and rotavirus-associated hospitalizations in California and New York, 2000-2005",

abstract = "Background: Kawasaki Syndrome (KS) is an uncommon childhood disease with unknown etiology. It has been suggested that rotavirus infection may play a causative role in the development of KS. Methods: To examine potential temporal associations between KS and rotavirus infection, seasonal patterns of KS- and rotavirus-associated hospitalizations among children in California and New York during 2000-2005 were compared. Results: Rotavirus hospital admissions were markedly winter seasonal, with very few summer hospitalizations. KS hospitalizations occurred year-round but also peaked slightly during winter and spring. Conclusion: The strong winter seasonal pattern of rotavirus clearly differed from the year-round pattern of KS hospitalizations. While the present study cannot completely rule out rotavirus as having a role in the development of KS, other agents must be involved in the etiology of KS.",

author = "Adam MacNeil and Holman, {Robert C.} and Yorita, {Krista L.} and Steiner, {Claudia A.} and Parashar, {Umesh D.} and Belay, {Ermias D.}",

note = "Funding Information: The authors thank the California Office of Statewide Health Planning & Development, and the New York State Department of Health for their support and participation in the Healthcare Cost and Utilization Project. Work was funded entirely by the Centers for Disease Control and Prevention. The authors had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.",

year = "2009",

month = oct,

day = "16",

doi = "10.1186/1471-2431-9-65",

language = "English (US)",

volume = "9",

pages = "65",

journal = "BMC Pediatrics",

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T1 - Evaluation of seasonal patterns of Kawasaki Syndrome- and rotavirus-associated hospitalizations in California and New York, 2000-2005

AU - MacNeil, Adam

AU - Holman, Robert C.

AU - Yorita, Krista L.

AU - Steiner, Claudia A.

AU - Parashar, Umesh D.

AU - Belay, Ermias D.

N1 - Funding Information: The authors thank the California Office of Statewide Health Planning & Development, and the New York State Department of Health for their support and participation in the Healthcare Cost and Utilization Project. Work was funded entirely by the Centers for Disease Control and Prevention. The authors had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

PY - 2009/10/16

Y1 - 2009/10/16

N2 - Background: Kawasaki Syndrome (KS) is an uncommon childhood disease with unknown etiology. It has been suggested that rotavirus infection may play a causative role in the development of KS. Methods: To examine potential temporal associations between KS and rotavirus infection, seasonal patterns of KS- and rotavirus-associated hospitalizations among children in California and New York during 2000-2005 were compared. Results: Rotavirus hospital admissions were markedly winter seasonal, with very few summer hospitalizations. KS hospitalizations occurred year-round but also peaked slightly during winter and spring. Conclusion: The strong winter seasonal pattern of rotavirus clearly differed from the year-round pattern of KS hospitalizations. While the present study cannot completely rule out rotavirus as having a role in the development of KS, other agents must be involved in the etiology of KS.

AB - Background: Kawasaki Syndrome (KS) is an uncommon childhood disease with unknown etiology. It has been suggested that rotavirus infection may play a causative role in the development of KS. Methods: To examine potential temporal associations between KS and rotavirus infection, seasonal patterns of KS- and rotavirus-associated hospitalizations among children in California and New York during 2000-2005 were compared. Results: Rotavirus hospital admissions were markedly winter seasonal, with very few summer hospitalizations. KS hospitalizations occurred year-round but also peaked slightly during winter and spring. Conclusion: The strong winter seasonal pattern of rotavirus clearly differed from the year-round pattern of KS hospitalizations. While the present study cannot completely rule out rotavirus as having a role in the development of KS, other agents must be involved in the etiology of KS.

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Evaluation of seasonal patterns of Kawasaki Syndrome- and rotavirus-associated hospitalizations in California and New York, 2000-2005

Abstract

ASJC Scopus subject areas

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