TY - JOUR
T1 - Evaluation of RxNorm for Medication Clinical Decision Support
AU - Freimuth, Robert R.
AU - Wix, Kelly
AU - Zhu, Qian
AU - Siska, Mark
AU - Chute, Christopher G.
PY - 2014
Y1 - 2014
N2 - We evaluated the potential use of RxNorm to provide standardized representations of generic drug name and route of administration to facilitate management of drug lists for clinical decision support (CDS) rules. We found a clear representation of generic drug name but not route of administration. We identified several issues related to data quality, including erroneous or missing defined relationships, and the use of different concept hierarchies to represent the same drug. More importantly, we found extensive semantic precoordination of orthogonal concepts related to route and dose form, which would complicate the use of RxNorm for drug-based CDS. This study demonstrated that while RxNorm is a valuable resource for the standardization of medications used in clinical practice, additional work is required to enhance the terminology so that it can support expanded use cases, such as managing drug lists for CDS.
AB - We evaluated the potential use of RxNorm to provide standardized representations of generic drug name and route of administration to facilitate management of drug lists for clinical decision support (CDS) rules. We found a clear representation of generic drug name but not route of administration. We identified several issues related to data quality, including erroneous or missing defined relationships, and the use of different concept hierarchies to represent the same drug. More importantly, we found extensive semantic precoordination of orthogonal concepts related to route and dose form, which would complicate the use of RxNorm for drug-based CDS. This study demonstrated that while RxNorm is a valuable resource for the standardization of medications used in clinical practice, additional work is required to enhance the terminology so that it can support expanded use cases, such as managing drug lists for CDS.
UR - http://www.scopus.com/inward/record.url?scp=84964315396&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84964315396&partnerID=8YFLogxK
M3 - Article
C2 - 25954360
AN - SCOPUS:84964315396
SN - 1559-4076
VL - 2014
SP - 554
EP - 563
JO - AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium
JF - AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium
ER -