Evaluation of Restricted Diffusion in Cylinders. Phosphocreatine in Rabbit Leg Muscle

P. Van Gelderen, D. Des Pres, P. C.M. Van Zijl, C. T.W. Moonen

Research output: Contribution to journalArticlepeer-review

128 Scopus citations

Abstract

Interpretation of NMR diffusion data is complicated in the presence of diffusion barriers. In this study, restricted diffusion in cylinders is evaluated. A method is presented to determine the diameter of the cylinder and the unrestricted diffusion coefficient from the dependence of the trace of the diffusion tensor with diffusion time. This method is valid even if the orientation of the cylinders is unknown and varies within the sample. An example is given for the diffusion of phosphocreatine in the cylindrically shaped fibers of rabbit skeletal muscle.

Original languageEnglish (US)
Pages (from-to)255-260
Number of pages6
JournalJournal of Magnetic Resonance, Series B
Volume103
Issue number3
DOIs
StatePublished - 1994

ASJC Scopus subject areas

  • General Engineering

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