A prospective study of 29 patients with diabetic neuropathy and 47 non-diabetic patients with tarsal tunnel syndrome were evaluated with computer-assisted neurosensory testing at three sites on the foot. The sensitivity and specificity of one-point static touch thresholds for identifying the presence of large fiber axonal loss was done using the calculated thresholds for monofilaments derived from their markings. The sensitivity for one-point static touch in identifying axonal loss was 33% for the 5.07, 38% for the 4.93, 50% for the 4.17, and 60% for the 4.08 monofilament-equivalent, with a specificity of 100% at each level. Therefore, one-point static touch testing, even using monofilaments thinner than 5.07, has a high percentage of false-negative results in identifying patients with axonal loss.
|Original language||English (US)|
|Number of pages||7|
|Journal||Journal of the American Podiatric Medical Association|
|State||Published - 2001|
ASJC Scopus subject areas
- Orthopedics and Sports Medicine