Evaluation of multiple methods for detection of gastrointestinal colonization of carbapenem-resistant organisms from rectal swabs

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Abstract

Rectal swabs from high-risk patients were screened for carbapenem-resistant organisms (CROs) using several methods. The direct MacConkey plate method was the most sensitive for CROs (95%), while chromID CARBA and the Check-Direct CPE screen assay were the most sensitive for the detection of carbapenemase-producing organisms (CPOs) (100%; all blaKPC). All methods had a specificity of >90% for CROs, and for CPOs, the specificity ranged from 85 to 98%. Broth enrichment methods performed poorly compared to direct inoculation methods, negating the need for the broth enrichment step.

Original languageEnglish (US)
Pages (from-to)1664-1667
Number of pages4
JournalJournal of clinical microbiology
Volume54
Issue number6
DOIs
StatePublished - Jun 2016

ASJC Scopus subject areas

  • Microbiology (medical)

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