Evaluation of free-breathing three-dimensional magnetic resonance coronary angiography with hybrid ordered phase encoding (HOPE) for the detection of proximal coronary artery stenosis

Nicholas H. Bunce, Permi Jhooti, Jennifer Keegan, Shelley L. Rahman, Catherine Bunce, David N. Firmin, Simon W. Davies, Christine H. Lorenz, Dudley J. Pennell

Research output: Contribution to journalArticlepeer-review

Abstract

We evaluated free-breathing, prospective navigator-gated, three-dimensional (3D) magnetic resonance coronary angiography (MRCA) with hybrid ordered phase-encoding (HOPE), in the detection of proximal coronary artery stenosis. The coronary arteries were imaged in 46 patients undergoing cardiac catheterization. The mean scan time was 48 minutes. The mean arterial length (mm) visualized was left main stem (LMS) 11.7 (SD 4.5), left anterior descending (LAD) 30.1 (SD 11.1), circumflex (LCx) 15.5 (SD 8.6), and right (RCA) 56.2 (SD 20.8). Twenty-three patients had coronary artery disease with 47 significant stenoses on cardiac catheterization. All LMS were normal on both catheterization and MRCA. MRCA sensitivity was highest for the LAD (89% CI 65%-99%) and RCA (76% CI 50%-93%), but lower for the LCx (50% CI 21%-79%). Specificity ranged from 72%-100%. Improvements in image quality, length of vessel seen, and specific imaging of the LCx are required for MRCA to become an alternative to cardiac catheterization.

Original languageEnglish (US)
Pages (from-to)677-684
Number of pages8
JournalJournal of Magnetic Resonance Imaging
Volume14
Issue number6
DOIs
StatePublished - 2001
Externally publishedYes

Keywords

  • Cardiac catheterization
  • Coronary artery stenosis
  • Hybrid ordered phase-encoding
  • Magnetic resonance coronary angiography
  • Prospective navigator-gated

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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