Evaluation of fractional errors in pixels and regions in a time of flight PET scanner

L. Cinotti, F. Lavenne, D. Le Bars, P. Landais, R. Campagnolo, O. Rousset, F. Mauguiere

Research output: Contribution to journalArticlepeer-review


The coefficient of variation (standard deviation over mean: s/m) was computed in regions of interest (ROIs) and compared to the value obtained in pixels in a time of flight PET scanner. Using a homogeneous cylindrical phantom, the authors collected events in list mode and reconstructed a dynamic series of 256*256 images for 0.5, 1, 2, 5, 10 and 50 (*106) events per image. Circular ROIs with the same and increasing sizes were drawn at different positions in the field of view. Using Hanning (cosine) filtered images, the s/m varied between 76 and 8.3% (103 and 14%) for pixels while it was at most 7.5% (9.2%) for ROIs. The s/m values were higher in the direct plane (DP) than in the cross plane (CP) due to its higher sensitivity. Two-way analysis of variance showed no ROI position effect in DP or CP separately but a significant count/pixel effect. s/m for pixels and for ROIs were linearly correlated to the expected noise to signal ratio calculated according to a published model. For ROI studies, cosine filtered images demonstrated a 22% higher s/m than Hanning filtered images.

Original languageEnglish (US)
Article number009
Pages (from-to)1113-1120
Number of pages8
JournalPhysics in medicine and biology
Issue number8
StatePublished - Dec 1 1993
Externally publishedYes

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


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