Evaluation of behavioral and social issues among Thai HIV vaccine trial volunteers

Darawan Thapinta, Richard A. Jenkins, David D. Celentano, Sorachai Nitayaphan, Puangmalee Buapunth, Attaporn Triampon, Patricia A. Morgan, Chirasak Khamboonruang, Chanmet Suwanarach, Yupadee Yutabootr, Somsri Ruckphaopunt, Siriporn Suwankiti, Vanida Tubtong, Wipada Cheewawat, John G. McNeil, Rodney A. Michael

Research output: Contribution to journalArticlepeer-review

Abstract

Behavioral and social issues were investigated in phase I/II preventive HIV vaccine trial volunteers in Thailand. These included risk behavior, HIV knowledge, distress, and social experiences associated with trial participation. Data were collected at baseline and at 4- and 8-month follow- up visits. Volunteers reported relatively low levels of risk behaviors at baseline and at the follow-up visits. About one fifth reported overtly negative reactions from family or friends. No problems with discrimination in employment, health care, or insurance were reported. Findings add to the evidence suggesting the feasibility of phase I/II prophylactic HIV vaccine trials with low-risk volunteers in Thailand.

Original languageEnglish (US)
Pages (from-to)308-314
Number of pages7
JournalJournal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Volume20
Issue number3
DOIs
StatePublished - Mar 1 1999

Keywords

  • Developing countries
  • HIV sexual risk behavior
  • HIV vaccine trials
  • Thailand

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Virology

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