@article{15f42dd940d74a0fad0665aa54607b92,
title = "Evaluation of a live attenuated human metapneumovirus vaccine in adults and children",
abstract = "We conducted a phase I clinical trial of an experimental live attenuated recombinant human metapneumovirus (HMPV) vaccine (rHMPV-Pa) sequentially in adults, HMPV-seropositive children, and HMPV-seronegative children, the target population for vaccination. rHMPV-Pa was appropriately restricted in replication in adults and HMPV-seropositive children but wasoverattenuated for HMPV-seronegative children.",
author = "Karron, {Ruth A.} and {San Mateo}, Jocelyn and Kimberli Wanionek and Collins, {Peter L.} and Buchholz, {Ursula J.}",
note = "Funding Information: Financial support. R. A. K., J. S. M., and K. W. were funded by the NIAID (contract HHS 272200900010C). U. J. B. and P. L. C. were funded by the Intramural Program of the NIAID. Funding Information: 1Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; and 2Respiratory Viruses Section, Laboratory of Infectious Diseases, National Institute of Allergy, Immunology, and Infectious Diseases, National Institutes of Health, Bethesda, Maryland Publisher Copyright: {\textcopyright} The Author(s) 2017. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved.",
year = "2018",
month = feb,
day = "19",
doi = "10.1093/jpids/pix006",
language = "English (US)",
volume = "7",
pages = "86--89",
journal = "Journal of the Pediatric Infectious Diseases Society",
issn = "2048-7193",
publisher = "Oxford University Press",
number = "1",
}