Evaluation of a home-delivery service for HIV-infected patients attending an inner London HIV treatment centre

D. Harte, Matthew Hamill, S. G. Edwards, A. J. Copas, J. Minton, V. L. Jones, E. Allason-Jones, I. G. Williams, R. F. Miller

Research output: Contribution to journalArticle

Abstract

Home delivery (HD) of medication is a goal of the Department of Health's Pharmacy in the Future; Implementing the NHS Plan. We evaluated the safety and effectiveness of an HD service for antiretroviral therapy (ART). Patients on ART with stable viral load (VL) <50 were identified. Comparison was made between patients using HD and those using the clinic-based pharmacy (CP). The primary endpoint was HIV virological failure (VF) (HIV VL >400 copies/mL on two consecutive occasions). Secondary endpoints included frequency of outpatient attendances (OPA) and an incidence of adverse events. Cumulative incidences (CulmIn) for each outcome event were calculated. Incidence-rate ratios (IRR) were obtained using Poisson regression. Of 1663 patients identified; 450 received HD and 1213 used CP. CuImIn of VF was =4% in those using HD and =7% in those using CP (IRR [95% confidence intervals, CI] =0.53, 0.32-0.90). HD patients had fewer OPA, less frequent blood test monitoring and less frequent abnormal liver function results (IRR [95% CI]= 0.63 [0.59-0.67] and 0.59 [0.53-0.67], 0.68 [0.65-0.71] and 0.64 [0.53-0.78], respectively). Patients deemed stable enough on social, psychological and medical grounds to receive HD of ART had a lower risk of VF, fewer OPA and no increase in adverse events when compared with patients using CP.

Original languageEnglish (US)
Pages (from-to)533-535
Number of pages3
JournalInternational Journal of STD and AIDS
Volume19
Issue number8
DOIs
StatePublished - Aug 1 2008
Externally publishedYes

Fingerprint

HIV
Incidence
Outpatients
Confidence Intervals
Therapeutics
Hematologic Tests
Viral Load
Psychology
Safety
Liver
Health

Keywords

  • Antiretroviral therapy
  • HIV
  • Home delivery
  • Patient choice

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Evaluation of a home-delivery service for HIV-infected patients attending an inner London HIV treatment centre. / Harte, D.; Hamill, Matthew; Edwards, S. G.; Copas, A. J.; Minton, J.; Jones, V. L.; Allason-Jones, E.; Williams, I. G.; Miller, R. F.

In: International Journal of STD and AIDS, Vol. 19, No. 8, 01.08.2008, p. 533-535.

Research output: Contribution to journalArticle

Harte, D, Hamill, M, Edwards, SG, Copas, AJ, Minton, J, Jones, VL, Allason-Jones, E, Williams, IG & Miller, RF 2008, 'Evaluation of a home-delivery service for HIV-infected patients attending an inner London HIV treatment centre', International Journal of STD and AIDS, vol. 19, no. 8, pp. 533-535. https://doi.org/10.1258/ijsa.2007.007311
Harte, D. ; Hamill, Matthew ; Edwards, S. G. ; Copas, A. J. ; Minton, J. ; Jones, V. L. ; Allason-Jones, E. ; Williams, I. G. ; Miller, R. F. / Evaluation of a home-delivery service for HIV-infected patients attending an inner London HIV treatment centre. In: International Journal of STD and AIDS. 2008 ; Vol. 19, No. 8. pp. 533-535.
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