Evaluation of a home-delivery service for HIV-infected patients attending an inner London HIV treatment centre

D. Harte, M. Hamill, S. G. Edwards, A. J. Copas, J. Minton, V. L. Jones, E. Allason-Jones, I. G. Williams, R. F. Miller

Research output: Contribution to journalArticle

Abstract

Home delivery (HD) of medication is a goal of the Department of Health's Pharmacy in the Future; Implementing the NHS Plan. We evaluated the safety and effectiveness of an HD service for antiretroviral therapy (ART). Patients on ART with stable viral load (VL) <50 were identified. Comparison was made between patients using HD and those using the clinic-based pharmacy (CP). The primary endpoint was HIV virological failure (VF) (HIV VL >400 copies/mL on two consecutive occasions). Secondary endpoints included frequency of outpatient attendances (OPA) and an incidence of adverse events. Cumulative incidences (CulmIn) for each outcome event were calculated. Incidence-rate ratios (IRR) were obtained using Poisson regression. Of 1663 patients identified; 450 received HD and 1213 used CP. CuImIn of VF was =4% in those using HD and =7% in those using CP (IRR [95% confidence intervals, CI] =0.53, 0.32-0.90). HD patients had fewer OPA, less frequent blood test monitoring and less frequent abnormal liver function results (IRR [95% CI]= 0.63 [0.59-0.67] and 0.59 [0.53-0.67], 0.68 [0.65-0.71] and 0.64 [0.53-0.78], respectively). Patients deemed stable enough on social, psychological and medical grounds to receive HD of ART had a lower risk of VF, fewer OPA and no increase in adverse events when compared with patients using CP.

Original languageEnglish (US)
Pages (from-to)533-535
Number of pages3
JournalInternational Journal of STD and AIDS
Volume19
Issue number8
DOIs
StatePublished - Aug 2008
Externally publishedYes

Keywords

  • Antiretroviral therapy
  • HIV
  • Home delivery
  • Patient choice

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Pharmacology (medical)
  • Infectious Diseases

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  • Cite this

    Harte, D., Hamill, M., Edwards, S. G., Copas, A. J., Minton, J., Jones, V. L., Allason-Jones, E., Williams, I. G., & Miller, R. F. (2008). Evaluation of a home-delivery service for HIV-infected patients attending an inner London HIV treatment centre. International Journal of STD and AIDS, 19(8), 533-535. https://doi.org/10.1258/ijsa.2007.007311