Evaluating options for utility-based kidney allocation: Viewpoint

Research output: Contribution to journalReview articlepeer-review

Abstract

Over the last 5 years, a number of utility-based allocation systems have been proposed in an effort to increase the life-prolonging potential of deceased donor kidneys in the United States. These have included various adaptations of age-matching and net benefit, including the Eurotransplant Senior Program, Life Years From Transplant, and several systems for avoiding extreme donor/recipient mismatch. However, utility-based allocation is complex and raises issues regarding choice of metric, appropriateness of certain factors for use in allocation, accuracy of prediction models, transparency and perception, and possible effects on donation rates. Changing the role of utility in kidney allocation will likely cause changes to efficiency, equity, predictability, autonomy, controversy, trust and live donation. In this manuscript, various allocation systems are discussed, and a framework is proposed for quantifying the goals of the transplant community and evaluating options for utility-based kidney allocation in this context.

Original languageEnglish (US)
Pages (from-to)1513-1518
Number of pages6
JournalAmerican Journal of Transplantation
Volume9
Issue number7
DOIs
StatePublished - Jul 1 2009

Keywords

  • Deceased donor kidney transplantation
  • LYFT
  • Organ allocation
  • Survival benefit

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

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