Etiology of acute respiratory infections in children in tropical southern india

T. Jacob John, Thomas Cherian, Mercy John

Research output: Contribution to journalArticle

Abstract

Nasopharyngeal secretions and throat-swab specimens from 809 children <6 years old with acute respiratory infection were examined by culture and indirect immunofluorescence for the presence of virus or viral antigen. Blood was cultured for the presence of bacteria in selected cases of lower respiratory infection (LRI); pleural fluid also was cultured in cases of empyema. Viruses were detected in 163 (49%) of 331 children with LRI. Respiratory syncytial virus (RSV) was the commonest agent isolated (106 children). Other viruses isolated included parainfluenza viruses (36 children), adenoviruses (12), and influenza viruses (five). Outbreaks of infection due to RSV occurred during August through October. Pneumonia was the commonest LRI encountered (178 children). Among children with pneumonia, viruses were detected in 65 (37%) of 178 children, and bacteria were isolated from 27 (18%) of the 147 children for whom blood cultures were done. Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus were the common bacterial pathogens isolated. In cases of empyema and pyopneumothorax, S. aureus was the commonest organism isolated. There were 116 children with bronchiolitis, 83 (72%) of whom had viral infections; the majority of these children (81%) had RSV infection. Croup was uncommon (eight cases) and was caused mainly by parainfluenza viruses.

Original languageEnglish (US)
Pages (from-to)S463-S469
JournalReviews of Infectious Diseases
Volume13
DOIs
StatePublished - Jan 1 1991
Externally publishedYes

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Respiratory Tract Infections
India
Viruses
Paramyxoviridae Infections
Empyema
Respiratory Syncytial Viruses
Staphylococcus aureus
Pneumonia
Croup
Bacteria
Respiratory Syncytial Virus Infections
Bronchiolitis
Viral Antigens
Haemophilus influenzae
Virus Diseases
Indirect Fluorescent Antibody Technique
Pharynx
Streptococcus pneumoniae
Orthomyxoviridae
Adenoviridae

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Etiology of acute respiratory infections in children in tropical southern india. / John, T. Jacob; Cherian, Thomas; John, Mercy.

In: Reviews of Infectious Diseases, Vol. 13, 01.01.1991, p. S463-S469.

Research output: Contribution to journalArticle

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