Etiologic agent of an epidemic of cutaneous leishmaniasis in Tolima, Colombia

Isabel Rodríguez-Barraquer, Rafael Góngora, Martín Prager, Robinson Pacheco, Luz Mery Montero, Adriana Navas, Cristina Ferro, Maria Consuelo Miranda, Nancy G. Saravia

Research output: Contribution to journalArticle

Abstract

American cutaneous leishmaniasis (ACL) has been characterized as a zoonotic disease. However, peridomestic and domestic transmission have been recorded in at least nine countries in Central and South America. The present study was undertaken to identify the etiologic agent of a peridomestic epidemic of ACL in the Department of Tourna, Colombia. Leishmania isolates were obtained during the diagnosis of 56 patients with ACL who consulted the local leishmaniasis control program in three municipalities in Tolima. Species were identified using monoclonal antibodies and isoenzyme electrophoresis. A total of 53 (94.6%) of 56 isolates were identified as Leishmania (Viannia) guyanensis. Three isolates (5.4%) were identified as L. (V.) panamensis. Leishmania (V.) guyanensis is the probable etiologic agent of the largest epidemic of cutaneous leishmaniasis recorded in Colombia. This species has not previously been reported outside the Amazon and southeastern regions of Colombia, and has not been described in the peridomestic setting or linked with an epidemic.

Original languageEnglish (US)
Pages (from-to)276-282
Number of pages7
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume78
Issue number2
StatePublished - Feb 2008
Externally publishedYes

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Cutaneous Leishmaniasis
Colombia
Leishmania guyanensis
Central America
Leishmaniasis
South America
Leishmania
Zoonoses
Isoenzymes
Electrophoresis
Monoclonal Antibodies

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Rodríguez-Barraquer, I., Góngora, R., Prager, M., Pacheco, R., Montero, L. M., Navas, A., ... Saravia, N. G. (2008). Etiologic agent of an epidemic of cutaneous leishmaniasis in Tolima, Colombia. American Journal of Tropical Medicine and Hygiene, 78(2), 276-282.

Etiologic agent of an epidemic of cutaneous leishmaniasis in Tolima, Colombia. / Rodríguez-Barraquer, Isabel; Góngora, Rafael; Prager, Martín; Pacheco, Robinson; Montero, Luz Mery; Navas, Adriana; Ferro, Cristina; Miranda, Maria Consuelo; Saravia, Nancy G.

In: American Journal of Tropical Medicine and Hygiene, Vol. 78, No. 2, 02.2008, p. 276-282.

Research output: Contribution to journalArticle

Rodríguez-Barraquer, I, Góngora, R, Prager, M, Pacheco, R, Montero, LM, Navas, A, Ferro, C, Miranda, MC & Saravia, NG 2008, 'Etiologic agent of an epidemic of cutaneous leishmaniasis in Tolima, Colombia', American Journal of Tropical Medicine and Hygiene, vol. 78, no. 2, pp. 276-282.
Rodríguez-Barraquer I, Góngora R, Prager M, Pacheco R, Montero LM, Navas A et al. Etiologic agent of an epidemic of cutaneous leishmaniasis in Tolima, Colombia. American Journal of Tropical Medicine and Hygiene. 2008 Feb;78(2):276-282.
Rodríguez-Barraquer, Isabel ; Góngora, Rafael ; Prager, Martín ; Pacheco, Robinson ; Montero, Luz Mery ; Navas, Adriana ; Ferro, Cristina ; Miranda, Maria Consuelo ; Saravia, Nancy G. / Etiologic agent of an epidemic of cutaneous leishmaniasis in Tolima, Colombia. In: American Journal of Tropical Medicine and Hygiene. 2008 ; Vol. 78, No. 2. pp. 276-282.
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