TY - JOUR
T1 - Ethnic variation in certain hematological and biochemical reference intervals in a south Indian healthy adult population
AU - Sundaram, M.
AU - Mohanakrishnan, J.
AU - Murugavel, K. G.
AU - Shankar, E. M.
AU - Solomon, S.
AU - Srinivas, C. N.
AU - Solomon, S. S.
AU - Pulimi, S.
AU - Piwowar-Manning, E.
AU - Dawson, S.
AU - Livant, E.
AU - Kumarasamy, N.
AU - Balakrishnan, P.
PY - 2008/1
Y1 - 2008/1
N2 - Background: We established the biochemical and hematological reference intervals among a south Indian healthy adult population attending an HIV referral centre in Chennai, southern India. Methods: In a cross sectional study, 213 study subjects (129 male and 84 female) were studied between March and August 2005. All of the parameters were analyzed using standard hematological and biochemical techniques. Results: Certain biochemical (viz. total bilirubin, alanine transaminase, albumin, creatinine, total protein, lipid profile, creatine phospokinase, uric acid and lactate) and hematological (mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and lymphocyte levels) parameters presented higher upper limits. In addition, the upper limits of white blood cell count, platelet count, hematocrit, red blood cell count and hemoglobin level were low in comparison to the currently reported ranges. Conclusion: Ethnic variation in reference intervals was observed in certain biochemical and hematological analytes in a south Indian adult population.
AB - Background: We established the biochemical and hematological reference intervals among a south Indian healthy adult population attending an HIV referral centre in Chennai, southern India. Methods: In a cross sectional study, 213 study subjects (129 male and 84 female) were studied between March and August 2005. All of the parameters were analyzed using standard hematological and biochemical techniques. Results: Certain biochemical (viz. total bilirubin, alanine transaminase, albumin, creatinine, total protein, lipid profile, creatine phospokinase, uric acid and lactate) and hematological (mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and lymphocyte levels) parameters presented higher upper limits. In addition, the upper limits of white blood cell count, platelet count, hematocrit, red blood cell count and hemoglobin level were low in comparison to the currently reported ranges. Conclusion: Ethnic variation in reference intervals was observed in certain biochemical and hematological analytes in a south Indian adult population.
KW - Biochemical and hematological parameters
KW - Clinical trials
KW - India
KW - Reference intervals
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U2 - 10.1016/j.ejim.2007.06.010
DO - 10.1016/j.ejim.2007.06.010
M3 - Article
C2 - 18206601
AN - SCOPUS:38349127030
SN - 0953-6205
VL - 19
SP - 46
EP - 50
JO - European Journal of Internal Medicine
JF - European Journal of Internal Medicine
IS - 1
ER -