Ethnic variation in certain hematological and biochemical reference intervals in a south Indian healthy adult population

M. Sundaram, J. Mohanakrishnan, K. G. Murugavel, E. M. Shankar, S. Solomon, C. N. Srinivas, S. S. Solomon, S. Pulimi, E. Piwowar-Manning, S. Dawson, E. Livant, N. Kumarasamy, P. Balakrishnan

Research output: Contribution to journalArticle

Abstract

Background: We established the biochemical and hematological reference intervals among a south Indian healthy adult population attending an HIV referral centre in Chennai, southern India. Methods: In a cross sectional study, 213 study subjects (129 male and 84 female) were studied between March and August 2005. All of the parameters were analyzed using standard hematological and biochemical techniques. Results: Certain biochemical (viz. total bilirubin, alanine transaminase, albumin, creatinine, total protein, lipid profile, creatine phospokinase, uric acid and lactate) and hematological (mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration and lymphocyte levels) parameters presented higher upper limits. In addition, the upper limits of white blood cell count, platelet count, hematocrit, red blood cell count and hemoglobin level were low in comparison to the currently reported ranges. Conclusion: Ethnic variation in reference intervals was observed in certain biochemical and hematological analytes in a south Indian adult population.

Original languageEnglish (US)
Pages (from-to)46-50
Number of pages5
JournalEuropean Journal of Internal Medicine
Volume19
Issue number1
DOIs
StatePublished - Jan 1 2008
Externally publishedYes

Keywords

  • Biochemical and hematological parameters
  • Clinical trials
  • India
  • Reference intervals

ASJC Scopus subject areas

  • Internal Medicine

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    Sundaram, M., Mohanakrishnan, J., Murugavel, K. G., Shankar, E. M., Solomon, S., Srinivas, C. N., Solomon, S. S., Pulimi, S., Piwowar-Manning, E., Dawson, S., Livant, E., Kumarasamy, N., & Balakrishnan, P. (2008). Ethnic variation in certain hematological and biochemical reference intervals in a south Indian healthy adult population. European Journal of Internal Medicine, 19(1), 46-50. https://doi.org/10.1016/j.ejim.2007.06.010