Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma

Catherine Igartua, Rachel A. Myers, Rasika Mathias, Maria Pino-Yanes, Celeste Eng, Penelope E. Graves, Albert M. Levin, Blanca E. Del-Rio-Navarro, Daniel J. Jackson, Oren E. Livne, Nicholas Rafaels, Christopher K. Edlund, James J. Yang, Scott Huntsman, Muhammad T. Salam, Isabelle Romieu, Raphael Mourad, James E. Gern, Robert F. Lemanske, Annah Wyss & 12 others Jane A. Hoppin, Kathleen C. Barnes, Esteban G. Burchard, W. James Gauderman, Fernando D. Martinez, Benjamin A. Raby, Scott T. Weiss, L. Keoki Williams, Stephanie J. London, Frank D. Gilliland, Dan L. Nicolae, Carole Ober

Research output: Contribution to journalArticle

Abstract

Common variants at many loci have been robustly associated with asthma but explain little of the overall genetic risk. Here we investigate the role of rare (

Original languageEnglish (US)
Article number5965
JournalNature Communications
Volume6
DOIs
StatePublished - 2015

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asthma
DNA sequences
loci
Asthma
deoxyribonucleic acid
low frequencies

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Chemistry(all)
  • Physics and Astronomy(all)

Cite this

Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma. / Igartua, Catherine; Myers, Rachel A.; Mathias, Rasika; Pino-Yanes, Maria; Eng, Celeste; Graves, Penelope E.; Levin, Albert M.; Del-Rio-Navarro, Blanca E.; Jackson, Daniel J.; Livne, Oren E.; Rafaels, Nicholas; Edlund, Christopher K.; Yang, James J.; Huntsman, Scott; Salam, Muhammad T.; Romieu, Isabelle; Mourad, Raphael; Gern, James E.; Lemanske, Robert F.; Wyss, Annah; Hoppin, Jane A.; Barnes, Kathleen C.; Burchard, Esteban G.; Gauderman, W. James; Martinez, Fernando D.; Raby, Benjamin A.; Weiss, Scott T.; Williams, L. Keoki; London, Stephanie J.; Gilliland, Frank D.; Nicolae, Dan L.; Ober, Carole.

In: Nature Communications, Vol. 6, 5965, 2015.

Research output: Contribution to journalArticle

Igartua, C, Myers, RA, Mathias, R, Pino-Yanes, M, Eng, C, Graves, PE, Levin, AM, Del-Rio-Navarro, BE, Jackson, DJ, Livne, OE, Rafaels, N, Edlund, CK, Yang, JJ, Huntsman, S, Salam, MT, Romieu, I, Mourad, R, Gern, JE, Lemanske, RF, Wyss, A, Hoppin, JA, Barnes, KC, Burchard, EG, Gauderman, WJ, Martinez, FD, Raby, BA, Weiss, ST, Williams, LK, London, SJ, Gilliland, FD, Nicolae, DL & Ober, C 2015, 'Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma', Nature Communications, vol. 6, 5965. https://doi.org/10.1038/ncomms6965
Igartua, Catherine ; Myers, Rachel A. ; Mathias, Rasika ; Pino-Yanes, Maria ; Eng, Celeste ; Graves, Penelope E. ; Levin, Albert M. ; Del-Rio-Navarro, Blanca E. ; Jackson, Daniel J. ; Livne, Oren E. ; Rafaels, Nicholas ; Edlund, Christopher K. ; Yang, James J. ; Huntsman, Scott ; Salam, Muhammad T. ; Romieu, Isabelle ; Mourad, Raphael ; Gern, James E. ; Lemanske, Robert F. ; Wyss, Annah ; Hoppin, Jane A. ; Barnes, Kathleen C. ; Burchard, Esteban G. ; Gauderman, W. James ; Martinez, Fernando D. ; Raby, Benjamin A. ; Weiss, Scott T. ; Williams, L. Keoki ; London, Stephanie J. ; Gilliland, Frank D. ; Nicolae, Dan L. ; Ober, Carole. / Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma. In: Nature Communications. 2015 ; Vol. 6.
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AU - Graves, Penelope E.

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AU - Barnes, Kathleen C.

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AU - Raby, Benjamin A.

AU - Weiss, Scott T.

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AU - London, Stephanie J.

AU - Gilliland, Frank D.

AU - Nicolae, Dan L.

AU - Ober, Carole

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