Abstract
Objective: To compare weight loss in blacks and whites in the Trial of Nonpharmacologic Interventions in the Elderly (TONE). Research Methods and Procedures: TONE enrolled 421 overweight white and 164 overweight black adults, 60 to 79 years old, with blood pressure well-controlled on a single, antihypertensive drug. Drug therapy withdrawal was attempted 3 months after randomization to counseling for weight loss, sodium reduction, both weight loss and sodium reduction, or to usual care, with follow-up for 15 to 36 months after enrollment. Statistical procedures included repeated measures analysis of covariance and logistic and proportional hazards regression. Results: In the weight-loss condition, net weight change (in kilograms) was -2.7 in blacks and -5.9 in whites (p < 0.001; ethnic difference, p = 0.0002) at 6 months and -2.0 (p < 0.05) in blacks and -4.9 (p < 0.001) in whites at the end of follow-up (ethnic difference, p = 0.007). In weight/ sodium, net weight change was -2.1 (p < 0.01) in blacks and -2.8 (p < 0.001) in whites at 6 months, and -1.9 in blacks and -1.7 in whites at the end of follow-up (p < 0.05; ethnic difference, p > 0.5). Exploratory analyses suggested a more favorable pattern of weight change in blacks than in whites from 6 months onward. There was no ethnic difference in blood pressure outcomes. Discussion: Whites lost more weight than blacks without, but not with, a concurrent focus on sodium reduction.
Original language | English (US) |
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Pages (from-to) | 96-106 |
Number of pages | 11 |
Journal | Obesity research |
Volume | 10 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2002 |
Keywords
- Aged
- Behavior change
- Blacks
- Blood pressure
- Cultural factors
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Food Science
- Endocrinology, Diabetes and Metabolism
- Endocrinology
- Public Health, Environmental and Occupational Health