Ethics and research assessing the relative roles of genes and the environment

Matthew DeCamp, Jeremy Sugarman

Research output: Contribution to journalReview articlepeer-review

Abstract

Research on the interaction of genes and the environment is revealing that many human diseases have both genetic and environmental components. Even traditional "environmental" diseases, such as infections, appear to interact with genetic components in the human host. Environmental genetics research will inevitably increase understanding of individual susceptibilities to toxic exposures in the environment and harmful side effects of medications; therefore, it has great promise for improving the prevention and treatment of human diseases. However, realizing the benefits of this research requires careful attention to ethical issues that are particularly relevant in this context. This article reviews some of the most pressing issues related to research design and methods, as well as from the application of research results (e.g., workplace genetic screening and legal toxic torts, personal medical responsibility, and the relationship between genetics and public health measures).

Original languageEnglish (US)
Pages (from-to)161-182
Number of pages22
JournalAccountability in Research
Volume11
Issue number3-4
DOIs
StatePublished - Jan 1 2004

Keywords

  • Environmental genetics
  • Ethics
  • Genetic research
  • Population genetics
  • Research standards
  • Research subjects

ASJC Scopus subject areas

  • Education
  • Library and Information Sciences

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