Ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing

Nikolajs Zeps, Tamra Lysaght, Ruth Chadwick, Alexandre Erler, Roger Foo, Simona Giordano, Poh San Lai, G. Owen Schaefer, Vicki Xafis, Wei Leong Chew, Jeremy Sugarman

Research output: Contribution to journalShort surveypeer-review

Abstract

Altering the human epigenome with gene-editing technology in attempt to treat a variety of diseases and conditions seems scientifically feasible. We explore some of the ethical and regulatory issues related to the clinical translation of human epigenetic editing arguing that such approaches should be considered akin to somatic therapies.

Original languageEnglish (US)
Pages (from-to)1652-1655
Number of pages4
JournalStem Cell Reports
Volume16
Issue number7
DOIs
StatePublished - Jul 13 2021

ASJC Scopus subject areas

  • Biochemistry
  • Genetics
  • Developmental Biology
  • Cell Biology

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