Ethical issues in human organoid and gastruloid research

Megan Munsie, Insoo Hyun, Jeremy Sugarman

Research output: Contribution to journalArticle

Abstract

Research involving human organoids and gastruloids involves ethical issues associated with their derivation as well as their current and future uses. These include unique issues related to the extent of maturation that can be achieved in vitro or through chimeric research, as well as fundamental ethical considerations such as those concerning the provenance of human biomaterials and the use of gene-editing technologies. Many of these issues are not specifically addressed by existing ethics oversight mechanisms, but these mechanisms might be easily extended to help ensure that human organoid and related research moves forward in an ethically appropriate manner.

Original languageEnglish (US)
Pages (from-to)942-945
Number of pages4
JournalDevelopment (Cambridge)
Volume144
Issue number6
DOIs
StatePublished - Mar 15 2017

Keywords

  • Chimera
  • Ethics
  • Gastruloids
  • Organoids
  • Regulation
  • Stem cells

ASJC Scopus subject areas

  • Molecular Biology
  • Developmental Biology

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