Ethical considerations in global HIV phylogenetic research

Ethics in HIV Phylogenetics Working Group

Research output: Contribution to journalReview article

Abstract

Phylogenetic analysis of pathogens is an increasingly powerful way to reduce the spread of epidemics, including HIV. As a result, phylogenetic approaches are becoming embedded in public health and research programmes, as well as outbreak responses, presenting unique ethical, legal, and social issues that are not adequately addressed by existing bioethics literature. We formed a multidisciplinary working group to explore the ethical issues arising from the design of, conduct in, and use of results from HIV phylogenetic studies, and to propose recommendations to minimise the associated risks to both individuals and groups. We identified eight key ethical domains, within which we highlighted factors that make HIV phylogenetic research unique. In this Review, we endeavoured to provide a framework to assist researchers, public health practitioners, and funding institutions to ensure that HIV phylogenetic studies are designed, done, and disseminated in an ethical manner. Our conclusions also have broader relevance for pathogen phylogenetics.

Original languageEnglish (US)
Pages (from-to)e656-e666
JournalThe Lancet HIV
Volume5
Issue number11
DOIs
StatePublished - Nov 1 2018

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HIV
Research
Public Health
Bioethics
Ethics
Disease Outbreaks
Research Personnel

ASJC Scopus subject areas

  • Epidemiology
  • Immunology
  • Infectious Diseases
  • Virology

Cite this

Ethical considerations in global HIV phylogenetic research. / Ethics in HIV Phylogenetics Working Group.

In: The Lancet HIV, Vol. 5, No. 11, 01.11.2018, p. e656-e666.

Research output: Contribution to journalReview article

Ethics in HIV Phylogenetics Working Group 2018, 'Ethical considerations in global HIV phylogenetic research', The Lancet HIV, vol. 5, no. 11, pp. e656-e666. https://doi.org/10.1016/S2352-3018(18)30134-6
Ethics in HIV Phylogenetics Working Group. / Ethical considerations in global HIV phylogenetic research. In: The Lancet HIV. 2018 ; Vol. 5, No. 11. pp. e656-e666.
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abstract = "Phylogenetic analysis of pathogens is an increasingly powerful way to reduce the spread of epidemics, including HIV. As a result, phylogenetic approaches are becoming embedded in public health and research programmes, as well as outbreak responses, presenting unique ethical, legal, and social issues that are not adequately addressed by existing bioethics literature. We formed a multidisciplinary working group to explore the ethical issues arising from the design of, conduct in, and use of results from HIV phylogenetic studies, and to propose recommendations to minimise the associated risks to both individuals and groups. We identified eight key ethical domains, within which we highlighted factors that make HIV phylogenetic research unique. In this Review, we endeavoured to provide a framework to assist researchers, public health practitioners, and funding institutions to ensure that HIV phylogenetic studies are designed, done, and disseminated in an ethical manner. Our conclusions also have broader relevance for pathogen phylogenetics.",
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