Abstract
Phylogenetic analysis of pathogens is an increasingly powerful way to reduce the spread of epidemics, including HIV. As a result, phylogenetic approaches are becoming embedded in public health and research programmes, as well as outbreak responses, presenting unique ethical, legal, and social issues that are not adequately addressed by existing bioethics literature. We formed a multidisciplinary working group to explore the ethical issues arising from the design of, conduct in, and use of results from HIV phylogenetic studies, and to propose recommendations to minimise the associated risks to both individuals and groups. We identified eight key ethical domains, within which we highlighted factors that make HIV phylogenetic research unique. In this Review, we endeavoured to provide a framework to assist researchers, public health practitioners, and funding institutions to ensure that HIV phylogenetic studies are designed, done, and disseminated in an ethical manner. Our conclusions also have broader relevance for pathogen phylogenetics.
| Original language | English (US) |
|---|---|
| Pages (from-to) | e656-e666 |
| Journal | The Lancet HIV |
| Volume | 5 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 1 2018 |
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ASJC Scopus subject areas
- Epidemiology
- Immunology
- Infectious Diseases
- Virology
Cite this
Ethical considerations in global HIV phylogenetic research. / Ethics in HIV Phylogenetics Working Group.
In: The Lancet HIV, Vol. 5, No. 11, 01.11.2018, p. e656-e666.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Ethical considerations in global HIV phylogenetic research
AU - Ethics in HIV Phylogenetics Working Group
AU - Coltart, Cordelia E.M.
AU - Hoppe, Anne
AU - Parker, Michael
AU - Dawson, Liza
AU - Amon, Joseph J.
AU - Simwinga, Musonda
AU - Geller, Gail
AU - Henderson, Gail
AU - Laeyendecker, Oliver B.
AU - Tucker, Joseph D.
AU - Eba, Patrick
AU - Novitsky, Vladimir
AU - Vandamme, Anne Mieke
AU - Seeley, Janet
AU - Dallabetta, Gina
AU - Harling, Guy
AU - Grabowski, Mary
AU - Godfrey-Faussett, Peter
AU - Fraser, Christophe
AU - Cohen, Myron S.
AU - Pillay, Deenan
AU - Amon, Joseph J.
AU - Baggaley, Rachel
AU - Bernard, Edwin J.
AU - Burns, David
AU - Cohen, Myron S.
AU - German, Danielle
AU - Dallabetta, Gina
AU - Dawson, Liza
AU - Dedes, Nikos
AU - Delpech, Valerie
AU - Eba, Patrick M.
AU - Fraser, Christophe
AU - Geller, Gail
AU - German, Danielle
AU - Godfrey-Faussett, Peter
AU - Grabowksi, M. Kate
AU - Hall, Irene
AU - Harling, Guy
AU - Henderson, Gail
AU - Hoppe, Anne
AU - Kozlakidis, Zisis
AU - Laeyendecker, Oliver
AU - Mwanza, Felix
AU - Novitsky, Vladimir
AU - Parker, Michael
AU - Pillay, Deenan
AU - Reis, Andreas
AU - Seeley, Janet
AU - Simwanga, Musonda
PY - 2018/11/1
Y1 - 2018/11/1
N2 - Phylogenetic analysis of pathogens is an increasingly powerful way to reduce the spread of epidemics, including HIV. As a result, phylogenetic approaches are becoming embedded in public health and research programmes, as well as outbreak responses, presenting unique ethical, legal, and social issues that are not adequately addressed by existing bioethics literature. We formed a multidisciplinary working group to explore the ethical issues arising from the design of, conduct in, and use of results from HIV phylogenetic studies, and to propose recommendations to minimise the associated risks to both individuals and groups. We identified eight key ethical domains, within which we highlighted factors that make HIV phylogenetic research unique. In this Review, we endeavoured to provide a framework to assist researchers, public health practitioners, and funding institutions to ensure that HIV phylogenetic studies are designed, done, and disseminated in an ethical manner. Our conclusions also have broader relevance for pathogen phylogenetics.
AB - Phylogenetic analysis of pathogens is an increasingly powerful way to reduce the spread of epidemics, including HIV. As a result, phylogenetic approaches are becoming embedded in public health and research programmes, as well as outbreak responses, presenting unique ethical, legal, and social issues that are not adequately addressed by existing bioethics literature. We formed a multidisciplinary working group to explore the ethical issues arising from the design of, conduct in, and use of results from HIV phylogenetic studies, and to propose recommendations to minimise the associated risks to both individuals and groups. We identified eight key ethical domains, within which we highlighted factors that make HIV phylogenetic research unique. In this Review, we endeavoured to provide a framework to assist researchers, public health practitioners, and funding institutions to ensure that HIV phylogenetic studies are designed, done, and disseminated in an ethical manner. Our conclusions also have broader relevance for pathogen phylogenetics.
UR - http://www.scopus.com/inward/record.url?scp=85057172173&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85057172173&partnerID=8YFLogxK
U2 - 10.1016/S2352-3018(18)30134-6
DO - 10.1016/S2352-3018(18)30134-6
M3 - Review article
C2 - 30174214
AN - SCOPUS:85057172173
VL - 5
SP - e656-e666
JO - The Lancet HIV
JF - The Lancet HIV
SN - 2352-3018
IS - 11
ER -