The effect of acute ethanol administration on plasma levels of β-endorphin-immunoreactivity and opioid activity was measured in 4 normal volunteers. 60 min following ethanol consumption opioid activity levels, measured by radioreceptor assay, increased significantly with peak rises of more than 400%; levels of β-endorphin-immunoreactivity did not change significantly. These results are compatible with the effect of the opiate-antagonist naloxone, reversing ethanol-induced coma.
|Original language||English (US)|
|Number of pages||2|
|Publication status||Published - 1981|
ASJC Scopus subject areas