Estimation of ventricular fiber orientations in infarcted hearts for patient-specific simulations

Fijoy Vadakkumpadan, Hermenegild Arevalo, Farhad Pashakhanloo, Anthony Alers, Fady Dawoud, Karl H. Schuleri, Daniel Herzka, Elliot McVeigh, Albert C. Lardo, Natalia Trayanova

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Patient-specific modeling of the heart is limited by lack of technology to acquire myocardial fiber orientations in the clinic. To overcome this limitation, we recently developed an image-based methodology to estimate the fiber orientations. In this study, we test the efficacy of that methodology in infarcted hearts. To this end, we implemented a processing pipeline to compare estimated fiber orientations of infarcted hearts with measured ones, and quantify the effect of the estimation error on outcomes of electrophysiological simulations. The pipeline was applied to images that we acquired from three infarcted canine hearts. The new insights obtained from the project will pave the way for the development of patient-specific models of infarcted hearts that can aid physicians in personalized diagnosis and decisions regarding electrophysiological interventions.

Original languageEnglish (US)
Title of host publicationProceedings - International Symposium on Biomedical Imaging
Pages636-639
Number of pages4
DOIs
StatePublished - 2013
Event2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013 - San Francisco, CA, United States
Duration: Apr 7 2013Apr 11 2013

Other

Other2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013
CountryUnited States
CitySan Francisco, CA
Period4/7/134/11/13

Fingerprint

Patient Simulation
Fiber reinforced materials
Pipelines
Error analysis
Canidae
Technology
Physicians
Processing

Keywords

  • atlas-based methods
  • magnetic resonance imaging
  • Physiological modeling

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

Cite this

Vadakkumpadan, F., Arevalo, H., Pashakhanloo, F., Alers, A., Dawoud, F., Schuleri, K. H., ... Trayanova, N. (2013). Estimation of ventricular fiber orientations in infarcted hearts for patient-specific simulations. In Proceedings - International Symposium on Biomedical Imaging (pp. 636-639). [6556555] https://doi.org/10.1109/ISBI.2013.6556555

Estimation of ventricular fiber orientations in infarcted hearts for patient-specific simulations. / Vadakkumpadan, Fijoy; Arevalo, Hermenegild; Pashakhanloo, Farhad; Alers, Anthony; Dawoud, Fady; Schuleri, Karl H.; Herzka, Daniel; McVeigh, Elliot; Lardo, Albert C.; Trayanova, Natalia.

Proceedings - International Symposium on Biomedical Imaging. 2013. p. 636-639 6556555.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Vadakkumpadan, F, Arevalo, H, Pashakhanloo, F, Alers, A, Dawoud, F, Schuleri, KH, Herzka, D, McVeigh, E, Lardo, AC & Trayanova, N 2013, Estimation of ventricular fiber orientations in infarcted hearts for patient-specific simulations. in Proceedings - International Symposium on Biomedical Imaging., 6556555, pp. 636-639, 2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013, San Francisco, CA, United States, 4/7/13. https://doi.org/10.1109/ISBI.2013.6556555
Vadakkumpadan F, Arevalo H, Pashakhanloo F, Alers A, Dawoud F, Schuleri KH et al. Estimation of ventricular fiber orientations in infarcted hearts for patient-specific simulations. In Proceedings - International Symposium on Biomedical Imaging. 2013. p. 636-639. 6556555 https://doi.org/10.1109/ISBI.2013.6556555
Vadakkumpadan, Fijoy ; Arevalo, Hermenegild ; Pashakhanloo, Farhad ; Alers, Anthony ; Dawoud, Fady ; Schuleri, Karl H. ; Herzka, Daniel ; McVeigh, Elliot ; Lardo, Albert C. ; Trayanova, Natalia. / Estimation of ventricular fiber orientations in infarcted hearts for patient-specific simulations. Proceedings - International Symposium on Biomedical Imaging. 2013. pp. 636-639
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