Estimation of segregation and ascertainment probabilities by discarding the single probands

C. C. Li, Aravinda Chakravarti, Susan L. Halloran

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5 Scopus citations


The first portion of this communication reiterates the method of discarding single probands for studying the segregation ratio under incomplete ascertainment. The organization of the algebra leads to the second portion, in which the “self-contained” subsets are constructed with respect to both the segregation ratio and the ascertainment ratio. These subsets make a more detailed study of segregation and ascertainment possible.

Original languageEnglish (US)
Pages (from-to)185-191
Number of pages7
JournalGenetic epidemiology
Issue number3
StatePublished - Jan 1 1987


  • ascertainment
  • proband
  • segregation ratio

ASJC Scopus subject areas

  • Epidemiology
  • Genetics(clinical)

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