Estimation of fiber orientations using neighborhood information

Chuyang Ye, Jiachen Zhuo, Rao P. Gullapalli, Jerry L. Prince

Research output: Contribution to journalArticlepeer-review

Abstract

Data from diffusion magnetic resonance imaging (dMRI) can be used to reconstruct fiber tracts, for example, in muscle and white matter. Estimation of fiber orientations (FOs) is a crucial step in the reconstruction process and these estimates can be corrupted by noise. In this paper, a new method called Fiber Orientation Reconstruction using Neighborhood Information (FORNI) is described and shown to reduce the effects of noise and improve FO estimation performance by incorporating spatial consistency. FORNI uses a fixed tensor basis to model the diffusion weighted signals, which has the advantage of providing an explicit relationship between the basis vectors and the FOs. FO spatial coherence is encouraged using weighted ℓ1-norm regularization terms, which contain the interaction of directional information between neighbor voxels. Data fidelity is encouraged using a squared error between the observed and reconstructed diffusion weighted signals. After appropriate weighting of these competing objectives, the resulting objective function is minimized using a block coordinate descent algorithm, and a straightforward parallelization strategy is used to speed up processing. Experiments were performed on a digital crossing phantom, ex vivo tongue dMRI data, and in vivobrain dMRI data for both qualitative and quantitative evaluation. The results demonstrate that FORNI improves the quality of FO estimation over other state of the art algorithms.

Original languageEnglish (US)
Pages (from-to)243-256
Number of pages14
JournalMedical image analysis
Volume32
DOIs
StatePublished - Aug 1 2016

Keywords

  • Diffusion MRI
  • Fiber orientation estimation
  • Neighborhood information

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Computer Vision and Pattern Recognition
  • Health Informatics
  • Computer Graphics and Computer-Aided Design

Fingerprint

Dive into the research topics of 'Estimation of fiber orientations using neighborhood information'. Together they form a unique fingerprint.

Cite this