Estimating the dose variation in a volume of interest with explicit consideration of patient geometric variation

David M. Lockman, Di Yan, John Wong

Research output: Contribution to journalArticlepeer-review

Abstract

A method to measure the effects of internal organ motion and deformation and patient setup error on cumulative dose variation in a volume of interest is proposed. The method uses multiple CT scans and electronic portal images of a single patient to numerically simulate dose-volume effects over the entire course of the patient's external beam treatment. The results are expressed in the form of a novel dose-volume histogram, called an expected dose-volume histogram (EDVH). (C) 2000 American Association of Physicists in Medicine.

Original languageEnglish (US)
Pages (from-to)2100-2108
Number of pages9
JournalMedical physics
Volume27
Issue number9
DOIs
StatePublished - Sep 2000
Externally publishedYes

Keywords

  • Dose-volume histogram
  • Organ deformation
  • Organ motion
  • Setup error
  • Stochastic processes

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

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