Estimates of world-wide distribution of child deaths from acute respiratory infections

Brian G. Williams; Eleanor Gouws; Cynthia Boschi-Pinto; Jennifer Bryce; Christopher Dye

doi:10.1016/S1473-3099(01)00170-0

Estimates of world-wide distribution of child deaths from acute respiratory infections

Brian G. Williams, Eleanor Gouws, Cynthia Boschi-Pinto, Jennifer Bryce, Christopher Dye

Research output: Contribution to journal › Review article › peer-review

599 Scopus citations

Abstract

Acute respiratory infections (ARI) are among the leading causes of childhood mortality. Estimates of the number of children worldwide who die from ARI are needed in setting priorities for health care. To establish a relation between deaths due to ARI and all-cause deaths in children under 5 years we show that the proportion of deaths directly attributable to ARI declines from 23% to 18% and then 15% (95% confidence limits range from ±:2% to ±3%) as under-5 mortality declines from 50 to 20 and then to 10/1000 per year. Much of the variability in estimates of ARI in children is shown to be inherent in the use of verbal autopsies. This analysis suggests that throughout the world 1·9 million (95% CI 1·6-2·2 million) children died from ARI in 2000, 70% of them in Africa and southeast Asia.

Original language	English (US)
Pages (from-to)	25-32
Number of pages	8
Journal	Lancet Infectious Diseases
Volume	2
Issue number	1
DOIs	https://doi.org/10.1016/S1473-3099(01)00170-0
State	Published - Jan 1 2002
Externally published	Yes

ASJC Scopus subject areas

Infectious Diseases

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10.1016/S1473-3099(01)00170-0

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title = "Estimates of world-wide distribution of child deaths from acute respiratory infections",

abstract = "Acute respiratory infections (ARI) are among the leading causes of childhood mortality. Estimates of the number of children worldwide who die from ARI are needed in setting priorities for health care. To establish a relation between deaths due to ARI and all-cause deaths in children under 5 years we show that the proportion of deaths directly attributable to ARI declines from 23% to 18% and then 15% (95% confidence limits range from ±:2% to ±3%) as under-5 mortality declines from 50 to 20 and then to 10/1000 per year. Much of the variability in estimates of ARI in children is shown to be inherent in the use of verbal autopsies. This analysis suggests that throughout the world 1·9 million (95% CI 1·6-2·2 million) children died from ARI in 2000, 70% of them in Africa and southeast Asia.",

author = "Williams, {Brian G.} and Eleanor Gouws and Cynthia Boschi-Pinto and Jennifer Bryce and Christopher Dye",

note = "Funding Information: We thank Claudia Stein, Michel Garenne, Kim Mulholland, and Robert Black for reviewing this paper and for their comments and suggestions. This work was supported by the World Health Organization Departments of Child and Adolescent Health and Development, and Vaccines and Biologicals. We have received no outside funding in support of this project, and have no conflicts of interest involving financial or personal relationships with other persons or organisations that could inappropriately influence the work. ",

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doi = "10.1016/S1473-3099(01)00170-0",

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T1 - Estimates of world-wide distribution of child deaths from acute respiratory infections

AU - Williams, Brian G.

AU - Gouws, Eleanor

AU - Boschi-Pinto, Cynthia

AU - Bryce, Jennifer

AU - Dye, Christopher

N1 - Funding Information: We thank Claudia Stein, Michel Garenne, Kim Mulholland, and Robert Black for reviewing this paper and for their comments and suggestions. This work was supported by the World Health Organization Departments of Child and Adolescent Health and Development, and Vaccines and Biologicals. We have received no outside funding in support of this project, and have no conflicts of interest involving financial or personal relationships with other persons or organisations that could inappropriately influence the work.

PY - 2002/1/1

Y1 - 2002/1/1

N2 - Acute respiratory infections (ARI) are among the leading causes of childhood mortality. Estimates of the number of children worldwide who die from ARI are needed in setting priorities for health care. To establish a relation between deaths due to ARI and all-cause deaths in children under 5 years we show that the proportion of deaths directly attributable to ARI declines from 23% to 18% and then 15% (95% confidence limits range from ±:2% to ±3%) as under-5 mortality declines from 50 to 20 and then to 10/1000 per year. Much of the variability in estimates of ARI in children is shown to be inherent in the use of verbal autopsies. This analysis suggests that throughout the world 1·9 million (95% CI 1·6-2·2 million) children died from ARI in 2000, 70% of them in Africa and southeast Asia.

AB - Acute respiratory infections (ARI) are among the leading causes of childhood mortality. Estimates of the number of children worldwide who die from ARI are needed in setting priorities for health care. To establish a relation between deaths due to ARI and all-cause deaths in children under 5 years we show that the proportion of deaths directly attributable to ARI declines from 23% to 18% and then 15% (95% confidence limits range from ±:2% to ±3%) as under-5 mortality declines from 50 to 20 and then to 10/1000 per year. Much of the variability in estimates of ARI in children is shown to be inherent in the use of verbal autopsies. This analysis suggests that throughout the world 1·9 million (95% CI 1·6-2·2 million) children died from ARI in 2000, 70% of them in Africa and southeast Asia.

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DO - 10.1016/S1473-3099(01)00170-0

M3 - Review article

C2 - 11892493

AN - SCOPUS:0036461410

SN - 1473-3099

VL - 2

SP - 25

EP - 32

JO - Lancet Infectious Diseases

JF - Lancet Infectious Diseases

IS - 1

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Estimates of world-wide distribution of child deaths from acute respiratory infections

Abstract

ASJC Scopus subject areas

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