Esophageal distensibility measurement: impact on clinical management and procedure length

N. K. Ahuja, A. Agnihotri, K. L. Lynch, D. Hoo-Fatt, F. Onyimba, M. McKnight, F. C. Okeke, Patricia Garcia, S. Dhalla, E. Stein, P. J. Pasricha, John O'Brien Clarke

Research output: Contribution to journalArticlepeer-review


Luminal distensibility measurement has demonstrated relevance to various disease processes, though its effects on clinical decision-making have been less well understood. This study aims to characterize the clinical impact of impedance planimetry measurement as well as the learning curve associated with its use in the esophagus. A single provider performed distensibility measurement in conjunction with upper endoscopy for a variety of clinical indications with the functional lumen imaging probe (FLIP) over a period of 21 months. Procedural data were prospectively collected and, along with medical records, retrospectively reviewed. Seventy-three procedures (70 patients) underwent esophageal distensibility measurement over the timeline of this study. The most common procedural indications were known or suspected achalasia (32.9%), dysphagia with connective tissue disease (13.7%), eosinophilic esophagitis (12.3%), and dysphagia with prior fundoplication (9.6%). FLIP results independently led to a change in management in 29 (39.7%) cases and supported a change in management in an additional 15 (20.5%) cases. The most common change in management was a new or amended therapeutic procedure (79.5%). Procedural time added by distensibility measurement was greater among earlier cases than among later cases. The median time added overall was 5 minutes and 46 seconds. Procedural time added varied significantly by procedural indication, but changes in management did not. Distensibility measurement added meaningful diagnostic information that impacted therapeutic decision-making in the majority of cases in which it was performed. Procedural time added by this modality is typically modest and decreases with experience.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalDiseases of the Esophagus
Issue number8
StatePublished - Aug 1 2017

ASJC Scopus subject areas

  • Gastroenterology


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