Erythrophagocytosis in the skin: case report

T. D. Horn, H. C. Hines, E. R. Farmer

Research output: Contribution to journalArticlepeer-review

Abstract

A 68‐year‐old male with a myclodysplastic syndrome developed a bulla on his right thigh. A skin biopsy revealed a subepider‐mal cleavage containing fibrin and a mononuclear cell infiltrate exhibiting prominent erylhrophagocytosis. Erythrophagocytosis by mononuclear cells was present, to a lesser extent, throughout the dermis and in the subcutis. Immunoperoxidase studies with anti‐lysozyme and anli‐alpha‐1‐chymotrysin confirmed the histiocytic nature of the phagocytic cells. Only a few prior reports of cutaneous erythrophagocytosis exist in the literature. In contrast to the generally grave clinical manifestations of the patients described in previous publications documenting erythrophagocytosis, this patient lacked a concomitant hematologic deterioration or serious systemic illness.

Original languageEnglish (US)
Pages (from-to)399-403
Number of pages5
JournalJournal of Cutaneous Pathology
Volume15
Issue number6
DOIs
StatePublished - Nov 1988

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Dermatology

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