Erythrocyte Fy antigen phenotyping helps differentiate so-called benign tertian malarias

Robert E. Wenk, Ina Stephens

Research output: Contribution to journalArticlepeer-review

Abstract

Isolated cases of malaria are increasing in frequency in nonendemic countries. Blood film examination remains a mainstay of diagnosis of these sporadic cases because immunologic and molecular methods are unavailable, expensive, and problematic. Two tertian malarial species, Plasmodium vivax and Plasmodium ovale, may appear to be similar morphologically. Plasmodium ovale infection is infrequent, and misdiagnosis of this species is common. Plasmodium vivax infection can be ruled out, however, if a patient's erythrocytes phenotype as Fy(a-b-), because these cells completely resist entry by the latter species.

Original languageEnglish (US)
Pages (from-to)299-301
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Volume124
Issue number2
StatePublished - Feb 23 2000

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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