Abstract
Patients with human immunodeficiency virus are known to have an increased risk for development of cutaneous malignant conditions. We present a 55-year-old man with a history of an isolated squamous-cell carcinoma five years prior, who presented with 27 cutaneous lesions, which had developed over the course of the preceding year. This occurred in the context of a new diagnosis of human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS). The initiation of anti-retroviral therapy and subsequent restoration of CD4 counts was associated with an increase in the number of lesions. Histopathologic examination of representative tumors showed basal-cell carcinomas, which lead to the diagnosis of eruptive basal-cell carcinomas in the setting of HIV-related immunosuppression. The incidence and epidemiology of malignant conditions that are related and non-related to AIDS are reviewed as well as discussion of the current literature regarding presentation, treatment, and prevention of non-melanoma skin cancers in patients with HIV infection.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1 |
| Number of pages | 1 |
| Journal | Dermatology Online Journal |
| Volume | 18 |
| Issue number | 12 |
| State | Published - Dec 2012 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Dermatology
Cite this
Eruptive basal-cell carcinomas in the setting of human immunodeficiency virus infection. / Spratt, Elizabeth A Gordon; Fischer, Max; Kamino, Hideko.
In: Dermatology Online Journal, Vol. 18, No. 12, 12.2012, p. 1.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Eruptive basal-cell carcinomas in the setting of human immunodeficiency virus infection
AU - Spratt, Elizabeth A Gordon
AU - Fischer, Max
AU - Kamino, Hideko
PY - 2012/12
Y1 - 2012/12
N2 - Patients with human immunodeficiency virus are known to have an increased risk for development of cutaneous malignant conditions. We present a 55-year-old man with a history of an isolated squamous-cell carcinoma five years prior, who presented with 27 cutaneous lesions, which had developed over the course of the preceding year. This occurred in the context of a new diagnosis of human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS). The initiation of anti-retroviral therapy and subsequent restoration of CD4 counts was associated with an increase in the number of lesions. Histopathologic examination of representative tumors showed basal-cell carcinomas, which lead to the diagnosis of eruptive basal-cell carcinomas in the setting of HIV-related immunosuppression. The incidence and epidemiology of malignant conditions that are related and non-related to AIDS are reviewed as well as discussion of the current literature regarding presentation, treatment, and prevention of non-melanoma skin cancers in patients with HIV infection.
AB - Patients with human immunodeficiency virus are known to have an increased risk for development of cutaneous malignant conditions. We present a 55-year-old man with a history of an isolated squamous-cell carcinoma five years prior, who presented with 27 cutaneous lesions, which had developed over the course of the preceding year. This occurred in the context of a new diagnosis of human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS). The initiation of anti-retroviral therapy and subsequent restoration of CD4 counts was associated with an increase in the number of lesions. Histopathologic examination of representative tumors showed basal-cell carcinomas, which lead to the diagnosis of eruptive basal-cell carcinomas in the setting of HIV-related immunosuppression. The incidence and epidemiology of malignant conditions that are related and non-related to AIDS are reviewed as well as discussion of the current literature regarding presentation, treatment, and prevention of non-melanoma skin cancers in patients with HIV infection.
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UR - http://www.scopus.com/inward/citedby.url?scp=84871505286&partnerID=8YFLogxK
M3 - Article
C2 - 23286791
AN - SCOPUS:84871505286
VL - 18
SP - 1
JO - Dermatology Online Journal
JF - Dermatology Online Journal
SN - 1087-2108
IS - 12
ER -