Eruptive basal-cell carcinomas in the setting of human immunodeficiency virus infection

Elizabeth A Gordon Spratt, Max Fischer, Hideko Kamino

Research output: Contribution to journalArticle

Abstract

Patients with human immunodeficiency virus are known to have an increased risk for development of cutaneous malignant conditions. We present a 55-year-old man with a history of an isolated squamous-cell carcinoma five years prior, who presented with 27 cutaneous lesions, which had developed over the course of the preceding year. This occurred in the context of a new diagnosis of human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS). The initiation of anti-retroviral therapy and subsequent restoration of CD4 counts was associated with an increase in the number of lesions. Histopathologic examination of representative tumors showed basal-cell carcinomas, which lead to the diagnosis of eruptive basal-cell carcinomas in the setting of HIV-related immunosuppression. The incidence and epidemiology of malignant conditions that are related and non-related to AIDS are reviewed as well as discussion of the current literature regarding presentation, treatment, and prevention of non-melanoma skin cancers in patients with HIV infection.

Original languageEnglish (US)
Pages (from-to)1
Number of pages1
JournalDermatology Online Journal
Volume18
Issue number12
StatePublished - Dec 2012
Externally publishedYes

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Basal Cell Carcinoma
Virus Diseases
HIV
Acquired Immunodeficiency Syndrome
Skin
Skin Neoplasms
CD4 Lymphocyte Count
Immunosuppression
Squamous Cell Carcinoma
Epidemiology
Incidence
Therapeutics
Neoplasms

ASJC Scopus subject areas

  • Dermatology

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Eruptive basal-cell carcinomas in the setting of human immunodeficiency virus infection. / Spratt, Elizabeth A Gordon; Fischer, Max; Kamino, Hideko.

In: Dermatology Online Journal, Vol. 18, No. 12, 12.2012, p. 1.

Research output: Contribution to journalArticle

Spratt, Elizabeth A Gordon ; Fischer, Max ; Kamino, Hideko. / Eruptive basal-cell carcinomas in the setting of human immunodeficiency virus infection. In: Dermatology Online Journal. 2012 ; Vol. 18, No. 12. pp. 1.
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