Eruptive basal-cell carcinomas in the setting of human immunodeficiency virus infection

Elizabeth A.Gordon Spratt, Max Fischer, Hideko Kamino

Research output: Contribution to journalArticlepeer-review

Abstract

Patients with human immunodeficiency virus are known to have an increased risk for development of cutaneous malignant conditions. We present a 55-year-old man with a history of an isolated squamous-cell carcinoma five years prior, who presented with 27 cutaneous lesions, which had developed over the course of the preceding year. This occurred in the context of a new diagnosis of human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS). The initiation of anti-retroviral therapy and subsequent restoration of CD4 counts was associated with an increase in the number of lesions. Histopathologic examination of representative tumors showed basal-cell carcinomas, which lead to the diagnosis of eruptive basal-cell carcinomas in the setting of HIV-related immunosuppression. The incidence and epidemiology of malignant conditions that are related and non-related to AIDS are reviewed as well as discussion of the current literature regarding presentation, treatment, and prevention of non-melanoma skin cancers in patients with HIV infection.

Original languageEnglish (US)
Number of pages1
JournalDermatology Online Journal
Volume18
Issue number12
StatePublished - Dec 1 2012

ASJC Scopus subject areas

  • Dermatology

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