Erratum: Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein (Proceedings of the National Academy of Sciences of the United States of America (2017) 114 (E10438–E10445) DOI: 10.1073/pnas.1715812114)

David Oyen, Jonathan L. Torres, Ulrike Wille-Reece, Christian F. Ockenhouse, Daniel Emerling, Jacob Glanville, Wayne Volkmuth, Yevel Flores-Garcia, Fidel Zavala, Andrew B. Ward, C. Richter King, Ian A. Wilson

Research output: Contribution to journalComment/debatepeer-review

Abstract

The authors note that they inadvertently omitted references that reported on computational models of helical structures for the NANP repeats of circumsporozoite protein (CSP) (1-3), one of which is a recent publication that used a helical model of (NANP)6 to explain the multivalent CSP binding of an anti-NANP antibody (3). The model described in Oyen et al., however, differs extensively from these previous models in that the NANP repeats adopt a wide, elongated spiral, compared for example to the tightly packed helix as described in ref. 3. The full references 1-3 appear below. The references should have been cited in an additional sentence, which should have appeared on page E10443, left column, first paragraph, to precede the sentence that begins on line 3 with “Many questions remain. . . .” The additional sentence should have appeared as follows: “Helical models have been predicted previously for the NANP repeats (1-3), but these differ substantially from the spiral conformation presented here.” The authors also note that Fig. S7 appeared incorrectly. The corrected Supporting figure and its legend appear below. The SI has been corrected online. (Figure Presented).

Original languageEnglish (US)
Pages (from-to)E5838-E5839
JournalProceedings of the National Academy of Sciences of the United States of America
Volume115
Issue number25
DOIs
StatePublished - Jun 19 2018

ASJC Scopus subject areas

  • General

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