Equatorial ring-like channels in the Cryptococcus neoformans polysaccharide capsule

Oscar Zaragoza, Erin E. Mcclelland, Andrew Telzak, Arturo Casadevall

Research output: Contribution to journalArticle

Abstract

Under certain conditions, India ink particles can penetrate the capsule of the opportunistic pathogen Cryptococcus neoformans. India ink penetration gave two distinct patterns, one as a ring in the middle of the capsule, and another as a double spot located at opposite poles of the cells. These spots were perpendicularly orientated to the bud. This pattern suggests the existence of a localized structure deep in the capsule that can accumulate large insoluble particles. Although the mechanisms responsible for the assemblage and maintenance of ring-like channels are not understood, their existence deep within the capsule implies a new level of complexity for this enigmatic structure.

Original languageEnglish (US)
Pages (from-to)662-666
Number of pages5
JournalFEMS Yeast Research
Volume6
Issue number4
DOIs
StatePublished - Jun 2006
Externally publishedYes

Fingerprint

Cryptococcus neoformans
Capsules
Polysaccharides
Maintenance
chinese ink

Keywords

  • Capsule
  • Channel
  • Cryptococcus neoformans
  • India Ink
  • Ring

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Microbiology
  • Infectious Diseases

Cite this

Equatorial ring-like channels in the Cryptococcus neoformans polysaccharide capsule. / Zaragoza, Oscar; Mcclelland, Erin E.; Telzak, Andrew; Casadevall, Arturo.

In: FEMS Yeast Research, Vol. 6, No. 4, 06.2006, p. 662-666.

Research output: Contribution to journalArticle

Zaragoza, Oscar ; Mcclelland, Erin E. ; Telzak, Andrew ; Casadevall, Arturo. / Equatorial ring-like channels in the Cryptococcus neoformans polysaccharide capsule. In: FEMS Yeast Research. 2006 ; Vol. 6, No. 4. pp. 662-666.
@article{a07eb4d00d434f01883993f3ab357454,
title = "Equatorial ring-like channels in the Cryptococcus neoformans polysaccharide capsule",
abstract = "Under certain conditions, India ink particles can penetrate the capsule of the opportunistic pathogen Cryptococcus neoformans. India ink penetration gave two distinct patterns, one as a ring in the middle of the capsule, and another as a double spot located at opposite poles of the cells. These spots were perpendicularly orientated to the bud. This pattern suggests the existence of a localized structure deep in the capsule that can accumulate large insoluble particles. Although the mechanisms responsible for the assemblage and maintenance of ring-like channels are not understood, their existence deep within the capsule implies a new level of complexity for this enigmatic structure.",
keywords = "Capsule, Channel, Cryptococcus neoformans, India Ink, Ring",
author = "Oscar Zaragoza and Mcclelland, {Erin E.} and Andrew Telzak and Arturo Casadevall",
year = "2006",
month = "6",
doi = "10.1111/j.1567-1364.2006.00070.x",
language = "English (US)",
volume = "6",
pages = "662--666",
journal = "FEMS Yeast Research",
issn = "1567-1356",
publisher = "Wiley-Blackwell",
number = "4",

}

TY - JOUR

T1 - Equatorial ring-like channels in the Cryptococcus neoformans polysaccharide capsule

AU - Zaragoza, Oscar

AU - Mcclelland, Erin E.

AU - Telzak, Andrew

AU - Casadevall, Arturo

PY - 2006/6

Y1 - 2006/6

N2 - Under certain conditions, India ink particles can penetrate the capsule of the opportunistic pathogen Cryptococcus neoformans. India ink penetration gave two distinct patterns, one as a ring in the middle of the capsule, and another as a double spot located at opposite poles of the cells. These spots were perpendicularly orientated to the bud. This pattern suggests the existence of a localized structure deep in the capsule that can accumulate large insoluble particles. Although the mechanisms responsible for the assemblage and maintenance of ring-like channels are not understood, their existence deep within the capsule implies a new level of complexity for this enigmatic structure.

AB - Under certain conditions, India ink particles can penetrate the capsule of the opportunistic pathogen Cryptococcus neoformans. India ink penetration gave two distinct patterns, one as a ring in the middle of the capsule, and another as a double spot located at opposite poles of the cells. These spots were perpendicularly orientated to the bud. This pattern suggests the existence of a localized structure deep in the capsule that can accumulate large insoluble particles. Although the mechanisms responsible for the assemblage and maintenance of ring-like channels are not understood, their existence deep within the capsule implies a new level of complexity for this enigmatic structure.

KW - Capsule

KW - Channel

KW - Cryptococcus neoformans

KW - India Ink

KW - Ring

UR - http://www.scopus.com/inward/record.url?scp=33646595299&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33646595299&partnerID=8YFLogxK

U2 - 10.1111/j.1567-1364.2006.00070.x

DO - 10.1111/j.1567-1364.2006.00070.x

M3 - Article

VL - 6

SP - 662

EP - 666

JO - FEMS Yeast Research

JF - FEMS Yeast Research

SN - 1567-1356

IS - 4

ER -