Epstein-Barr virus infection and neoplasia

P. M. Sprinkle, R. W. Veltri

Research output: Contribution to journalArticlepeer-review


Once acquired, Epstein-Barr virus (EBV), a latent virus, remains in the body for what appears to be the lifetime of the human host. Circumstantial data suggest EBV is involved in clinical disease including malignancies far more often than previously recognized. A serologic test for early antigen (EA) is more specific for diagnosing active EBV disease than the monospot or heterophile test. A case study of active Epstein-Barr infection is reported showing persistently elevated early antigen titers prior to and following malignant transformation.

Original languageEnglish (US)
Pages (from-to)542-544
Number of pages3
JournalOtolaryngology - Head and Neck Surgery
Issue number4
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


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