Epstein-Barr virus infection and neoplasia

P. M. Sprinkle; R. W. Veltri

doi:10.1177/019459988108900406

Epstein-Barr virus infection and neoplasia

P. M. Sprinkle, R. W. Veltri

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Once acquired, Epstein-Barr virus (EBV), a latent virus, remains in the body for what appears to be the lifetime of the human host. Circumstantial data suggest EBV is involved in clinical disease including malignancies far more often than previously recognized. A serologic test for early antigen (EA) is more specific for diagnosing active EBV disease than the monospot or heterophile test. A case study of active Epstein-Barr infection is reported showing persistently elevated early antigen titers prior to and following malignant transformation.

Original language	English (US)
Pages (from-to)	542-544
Number of pages	3
Journal	Otolaryngology - Head and Neck Surgery
Volume	89
Issue number	4
DOIs	https://doi.org/10.1177/019459988108900406
State	Published - 1981
Externally published	Yes

ASJC Scopus subject areas

Surgery
Otorhinolaryngology

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abstract = "Once acquired, Epstein-Barr virus (EBV), a latent virus, remains in the body for what appears to be the lifetime of the human host. Circumstantial data suggest EBV is involved in clinical disease including malignancies far more often than previously recognized. A serologic test for early antigen (EA) is more specific for diagnosing active EBV disease than the monospot or heterophile test. A case study of active Epstein-Barr infection is reported showing persistently elevated early antigen titers prior to and following malignant transformation.",

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AB - Once acquired, Epstein-Barr virus (EBV), a latent virus, remains in the body for what appears to be the lifetime of the human host. Circumstantial data suggest EBV is involved in clinical disease including malignancies far more often than previously recognized. A serologic test for early antigen (EA) is more specific for diagnosing active EBV disease than the monospot or heterophile test. A case study of active Epstein-Barr infection is reported showing persistently elevated early antigen titers prior to and following malignant transformation.

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Epstein-Barr virus infection and neoplasia

Abstract

ASJC Scopus subject areas

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