Epithelioid granuloma in the iris of a lepromatous leprosy patient; an unusual finding

E. Daniel, G. J. Ebenezer, T. J. Ffytche, A. Sigamani, C. K. Job

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


This case report depicts a case of histopathologically confirmed polar lepromatous (LL) leprosy with a bacterial index of 4+. He experienced recurrent episodes of erythema nodosum leprosum (ENL) in the first 5 years after diagnosis. Skin smears became negative after 6 years of dapsone monotherapy and have remained negative since that time. At 23 years after diagnosis, the patient had developed cataracts and underwent intracapsular cataract extractions with broad-based iridectomies. In one of the iris specimens, histopathologic examination revealed a focal granuloma composed of epithelioid cells. Subsequently a lepromin skin test showed a positive Mitsuda reaction with a borderline tuberculoid histopathology. This clearly illustrates the immunological upgrading of a polar lepromatous patient, perceived first in the iris tissue.

Original languageEnglish (US)
Pages (from-to)152-155
Number of pages4
JournalInternational Journal of Leprosy and Other Mycobacterial Diseases
Issue number2
StatePublished - Jan 1 2000
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology


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