Episodic secretion of luteinizing and follicle-stimulating hormones in agonadal and hypogonadal adolescents and adults

Allen Root, Allen Decherney, David Russ, Gregory Duckett, Celso Ramon Garcia, Edward Wallach

Research output: Contribution to journalArticlepeer-review

Abstract

Serum concentrations of luteinizing hormone (LH) and follicle stimulating hormone (FSH) were determined in specimens obtained sequentially at IS- or 20-min intervals for six- or eight-hr periods in: girls of adolescent age with gonadal dysgenesis (N-4); ovariectomized adult females (N-5); a post-menopausal woman; agonadal young adult males (N-2); and one subject with Klinefelter’s syndrome. LH levels oscillated significantly in each of these patients. FSH concentrations also varied in the majority of subjects, although the oscillations were not as marked as those of LH. FSH and LH fluctuations were often, but not always, synchronous. It is suggested that the rhythmic oscillations in peripheral gonadotropin levels reflect intermittent stimulation of pituitary secretion by the hypothalamic gonadotropin releasing hormone(s).

Original languageEnglish (US)
Pages (from-to)700-704
Number of pages5
JournalJournal of Clinical Endocrinology and Metabolism
Volume35
Issue number5
DOIs
StatePublished - Jan 1 1972
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

Fingerprint Dive into the research topics of 'Episodic secretion of luteinizing and follicle-stimulating hormones in agonadal and hypogonadal adolescents and adults'. Together they form a unique fingerprint.

Cite this